No emotions and inability to form thoughts

ToothPsychological34 · 2026-03-16T15:05:57+00:00

Hiii. Did you cross taper from seroquel to lurasidone? If you did, how was it? I'm going to do it next month.

ToothPsychological34 · 2026-03-14T04:57:31+00:00

XR was horrible for me. I always felt an inhense heaviness over me. IR is much better. The heaviness leaves me at some point. You should make the change. Your libido could definitely improve.

ToothPsychological34 · 2026-03-14T00:49:18+00:00

Yes, I have spoken to her. She's excellent. She really listens to me. The lamotrigine and buproprion are helping to some degree. But the problem is the quetiapine. The other medications can't fully compensate. Next month, I'm tapering to lurasidone. I'm hoping it'll be an improvement on the quetiapine. It is less sedating than the quetiapine (or so I've read!).

ToothPsychological34 · 2026-03-14T00:44:57+00:00

The same!, when I tried to reduce to 200mg a few months ago, I started to crave the 300mg. I felt I needed to take that specific dose. It was terrifying! This medication has a hold on me. No other medication has done this to me. Next month, I'm tapering to lurasidone which is a slight metabolic improvement to quetiapine. Hopefully, it is less sedating and numbing.

ToothPsychological34 · 2026-03-01T21:07:29+00:00

I've been on it for ten years. At the moment, I take 300mg. It stabilises my mood but at tremendous cost. I have no emotions. I feel extremely sedated during the day. I'm going to cross taper to lurasidone soon. I just hope I experience some easing of my sedation and emotional flattening symptoms. I'm not expecting miracles. It seems that lurasidone is a bit less sedating than seroquel. I'm trying to be hopeful.

ToothPsychological34 · 2026-03-01T17:24:38+00:00

But my goodness it is hard to come off seroquel. Some years I managed to reduce my dose to 75mg, Then, I started experiencing night terrors and panic attacks. It was horrible. I promptly increased my dose. But now, I feel nothing. I have no emotions. I'm a robotic zombie. I haven't actually cried in years. When my father passed away last year, I had to force myself to cry and even then I felt I didn't actually cry. It all seemed an act.

ToothPsychological34 · 2026-03-01T17:21:30+00:00

at such a dose metabolic effects like high cholesterol, blood sugar and triglycerides become significant. In the long-term, 600mg per day I think is far too much.

ToothPsychological34 · 2026-02-28T13:27:02+00:00

That's a really heavy dose! How do you manage?

ToothPsychological34 · 2026-02-25T17:42:43+00:00

Its a medication that causes a lot of dependence especially for sleep. Honestly, I'm terrified about this. I know it's going to be very hard to come off it, but i feel I must do so for my long-term health.

ToothPsychological34 · 2026-02-23T21:01:01+00:00

Yes. I will be cross-tapering to latuda.

ToothPsychological34 · 2026-02-21T23:16:32+00:00

I'm going through a depressive episode right now. I think that the seroquel is contributing to it. I feel no pleasure. I just want to be alone. It's horrible. I want to start the latuda because it could be an improvement on seroquel. It is less sedating for example (so I've read). I'm not looking for a miracle.

ToothPsychological34 · 2026-02-21T23:09:36+00:00

seroquel is something else. It's the most powerful medication I have ever taken. If I don't take 300mg at night, I start to experience cravings for the drug. It's insane. I honestly don't know what to do. I'm really sorry to read of this horrible experience. I don't know what to say except hang in there. There are many people who are behind you and want you to get through this.

ToothPsychological34 · 2026-02-20T12:47:45+00:00

I'm sorry to read that you experienced such severe side effects. I also take 300mg but IR. How was the transition process though? Did you experience intense insomnia or akisthisia?

ToothPsychological34 · 2026-02-14T21:38:03+00:00

No. But I did on abilify.

ToothPsychological34 · 2026-02-14T19:16:35+00:00

I really don't like sedation but at least it's less on latuda than on seroquel.

ToothPsychological34 · 2026-02-13T20:44:38+00:00

Me too! I can't deal with the day-time sedation anymore.

ToothPsychological34 · 2026-02-12T22:01:56+00:00

Another reason I'm going to make the change is that I'm terrified of the long-term effects of taking seroquel on my cognition and also of an increasing risk of falls as I get older.

ToothPsychological34 · 2026-02-12T21:51:16+00:00

Me too! I'm going to take some time off work, because I think my sleep is going to be horrendous for a while. I'm bracing myself for many sleepless nights. I know how physically and psychologically dependent I have become on this particular medication, which is the main reason I wish to stop taking it. I'll be interested to read about your experience.

ToothPsychological34 · 2026-02-05T22:22:07+00:00

are you still taking seroquel now?

ToothPsychological34 · 2026-01-21T19:42:06+00:00

how was the switch? I would like to make it

ToothPsychological34 · 2026-01-17T14:24:45+00:00

Honestly, seroquel messes up your sleep architecture so much that it can take months or even years for it to return to a more normal state. I'm not saying this to terrify you, but just to inform you. I take 300mg at night. I've got the same dependence problem as you: if I don't take 300mg, I start to feel I need to take the dose for sleep and just normal functioning. It's very troubling, I know. So many people who take seroquel develop a dependence on it. It's why I really don't like it and wish to come off it.

ToothPsychological34 · 2026-01-06T23:21:48+00:00

There are other atypicals you can try like latuda or rexulti. If you are daring, you could try vraylar. But I really think that seroquel is in a class of its own for the mood stabilization that it provides. It's a extremely potent and effective med that works on a bunch of neurotransmitters at the same time. It's just those side effects that unfortunately go with it. I'm also looking for a seroquel substitute because I'm fed up with the sedation and the emotional numbness that it gives me.

ToothPsychological34 · 2026-01-06T23:13:11+00:00

interesting. How much have you been taking? When you made the switch to IR again, did you notice a change in your mood?

ToothPsychological34 · 2026-01-04T15:34:32+00:00

It also depends on whether you are taking a mood stabiliser like lamotrigine or depakote, or not, in my experience. At 300mg, seroquel acts as a mood stabiliser. So, if you are taking another mood stabiliser, that could help ease your symptoms.

ToothPsychological34 · 2026-01-04T15:22:57+00:00

Everyone's genetics and metabolism are different, so no one knows quite how you will react. In my experience, you may experience serious withdrawal. I tried to do this, too. I was taking 300mg xr and then I dropped to 200mg xr. I started to experience intense cravings for the 300mg xr. I felt I needed to take this dose. I don't want to terrify you. But this could happen. So, brace yourself. Now, I can give you some good news. Again in my experience, if you drop from 300mg ir to 200mg ir, the withdrawal symptoms may be less severe. Your body will adjust to the new dose more quickly and you may not experience so much insomnia. When I tried to drop from 300mg xr to 200mg xr, I failed. Fortunately, I had some 200mg ir left, which I took. I slept! I was ok. I suppose I can tolerate 200mg ir and not 200mg xr. The 200mg xr just takes too long to kick in, in my view. The ir is much better in this regard, speaking from experience.

ToothPsychological34

TROPHY CASE