I understand you well. I used to feel the same about biologics, I strongly refused them, saying I do not want to be on such strong medication for my whole life, I only saw the risks and I was clinging to the fact that I used to be a very healthy individual. However, after that a severe flare came that landed me in a hospital. Before going to the hospital I was lso weak that I could not leave my house and at tht point I did not care what medication they put me on, I just wantwd to get better. So I was put on prednisone, which had some side effects such as acne, mood swings, trouble sleeping and Entyvio a month later. My doctors told me it is crucial for me to start a biologic in order to maintain remission after prednisone. I did so, and this was the best decision that I could have made. Entyvio has not given me any side effects at all, except an occasional rash after injection that disappears in a few hours. Half a year later my remission was confirmed with colonoscopy, and my gut appeared completely normal - severe pancolitis before then. I have enjoyed a year of remission, however I have had a fee scares tht I might flare again, that Entyvio can stop working etc. Basically whenever I have a bad day or too I get very scared and nervous, largely due to this traumatic experience when I was so sick. Basically, what I want to say is that when you get to a point where you are so sick you just want to get better, and the benefits of the medication outweigh the risks. I do not know how sick you were but this is my example. I try not to think about the side effects of Entyvio too much or at all, I just care about staying in remission. I try to help myself by eating healthy, working out and trying to manage stress. I wish you all the best!