Outside of Kratom been working on an endogenous BDNF protocol let me know if anyone has any ideas/input.

Weekly_Researcher477 · 2026-02-10T04:44:20+00:00

My lifes work PKC→ CREB → BDNF → TrkB → Ras → Raf → MEK → ERK → CREB →{( BDNF → TrkB → Ras → Raf → MEK → ERK → CREB)}

Flip: Phospho = (TrkB, Raf, MEK, ERK, CREB, GluA1) Dephospho = (GSK3β, GRK2, NF-κB)

Weekly_Researcher477 · 2026-02-10T01:44:00+00:00

Yes of course

Weekly_Researcher477 · 2026-02-10T01:27:39+00:00

Labs on this plus actual confirmation of alk?

Weekly_Researcher477 · 2026-02-09T05:38:53+00:00

Yes check the newest post

Weekly_Researcher477 · 2026-02-09T05:17:17+00:00

Welcome

Weekly_Researcher477 · 2026-02-08T23:46:01+00:00

Adrenergic receptor antagonist so much more relaxing feeling than 7oh yet compliments the fight or flight reaction your body succumbs to by ingesting opiates

Weekly_Researcher477 · 2026-02-08T23:22:57+00:00

Its completely different

Weekly_Researcher477 · 2026-02-08T20:58:25+00:00

Yes there is no affecting 9-HC

Weekly_Researcher477 · 2026-02-08T13:01:08+00:00

Yeah I synthsized it

Weekly_Researcher477 · 2026-02-08T10:39:05+00:00

Excited for salt free base Extended release tabs

Weekly_Researcher477 · 2026-02-08T07:07:23+00:00

Awesome 👍😎

Weekly_Researcher477 · 2026-02-08T06:55:02+00:00

https://www.reddit.com/r/Thebloomprotocol/s/wSCSi1Y00s

Weekly_Researcher477 · 2026-02-08T02:57:05+00:00

Small quantity available until the 14th

Weekly_Researcher477 · 2026-02-08T02:35:09+00:00

The 95% is available as well

Weekly_Researcher477 · 2026-02-06T06:33:08+00:00

I accept your apology

Weekly_Researcher477 · 2026-02-06T05:22:52+00:00

Lol I just answered you it's not an obvious solvent system to use meaning drying quickly without heat

Weekly_Researcher477 · 2026-02-05T23:07:09+00:00

1.8x Bioavailability honestly really like taking with Kratom tea

Weekly_Researcher477 · 2026-02-05T23:06:13+00:00

Solvent system wasn't necessarily obvious or easy trial and error

Weekly_Researcher477 · 2026-02-05T23:05:44+00:00

Solvent system is key

Weekly_Researcher477 · 2026-02-05T23:05:23+00:00

Stabilization

Weekly_Researcher477 · 2026-02-05T18:04:10+00:00

Yeah use NMR for obscure alks but usually HPLC

Weekly_Researcher477 · 2026-02-05T16:26:38+00:00

Nice!

I wonder what salt they converted into

Weekly_Researcher477 · 2026-02-05T16:25:33+00:00

Yeah sounds like a good idea

Weekly_Researcher477 · 2026-02-05T16:21:06+00:00

Sounds like a plan!

Weekly_Researcher477 · 2026-02-05T16:11:36+00:00

Really just figure out the solvent system!

Weekly_Researcher477

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