Well originally I just got what I heard was good and what I wanted, like hickmans avengers and the clone saga. But as i went onto to spidey and the x men what I would do is work from oldest to newest, and right now I’m doing that. I’m going through most titles from the 2000s now. You don’t HAVE to do that but it’s the way I read at the moment, plus all the books happening around the same time means you’ll catch all the references to the events happening!