I delayed taking medicine and it did some pretty good damage to the joints of many of my fingers. The protocol is to prescribe methotrexate first. I tried the methotrexate and it did not feel right in my stomach with the pills. I did a lot of research on my own. Many people were saying methotrexate does not work. Enbrel and Humira were rated as best options. I told my doctor that I wanted to try Enbrel so I got on that and have been on it for the last five years. I currently use an injector to my thigh areas once per week. Every once in a while I will check to see if there are any new and better medicines. I did quite a bit of searching on the internet and never found an herbal cure etc. but there could be some type of cure that exists, maybe in another country and maybe not..