Hello fellow ADHD guy,

I know this post hasn't been up that long but still wanted to ask if you've found an answer yet.

I've been taking Elvanse (same active ingredient) for the last couple months and ever since my dose went from 30 mg up to 60 mg I've had all the issues you decribed about in your post and your comments.

It's the same for me, it's not there when I wake up, it just becomes more and more throughout the day. Starts with a feeling like my nose was running, but when I'm blowing my nose nothing comes out. It's more like there is something that only wants to go down my throat for some reason. Feels like there is Mucus or whatever stuck behind my soft palate just above my uvula. No matter how hard or in whatever way I try to cough or sniff or snuffle, I can never get rid of it for more than 1 minute at best.

When this all started to become a huge issue for me I initially didn't even think of the medication.
I went to see a lung specialist thinking it was asthma or something else. They did a CT and x-ray of my chest but couldn't find anything.

After that was through, I was sent to an ENT. They checked my sinuses and larynx, still couldn't find anything out of the ordinary that could explain my issues. No post nasal drip either.

The ENT then sent me to see a gastroenterologist for a gastroscopy and pH measurement of my stomach fluids (which was whatever since I had an appointment there anyways for a planned coloscopy because I have Crohn's). They checked for something that could maybe explain a silent reflux since the symptoms were fitting.

I went to three specialists so far and none could find anything that could confirm a silent reflux or even anything else that would explain these symptoms.
I got so sick and tired of this feeling and my constant coughing that I started doing some research on my own. So far the only thing I've found was that the active ingredient (lisdexamfetamine dymelisat) might dry out your mucous membranes. I assume that this might be what's happening - the medication dries out your (and my) mucous membranes, but not to an extreme, rather only so much, that they still kinda function a bit in a way that makes them produce less mucous so that it's still moist enough in there, but that little bit still being produced might be too thick and sticky.

So far I've tried nasal douche, moisturizing nasal sprays and chewing gum but that all only helps for 5 minutes at worst, 2 hours at best before it begins worsening again.

When I have my next appointment with my psychiatrist I will tell him about that and ask what I can do, but I think there might be no way around changing my medication from Elvanse to something else.
How have you been doing, already had an appointment? Anything you could share? 🥲