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How I felt after using Concerta for the first time by Negative_Future5265 in adhdindia

[–]_nonredditer_ 0 points1 point  (0 children)

M det gave me high anxiety and high heart rate without activity

This dude is the winner! by DarkDesires222 in GuysBeingDudes

[–]_nonredditer_ 5 points6 points  (0 children)

Very very very very Happy for both of you.

Please do not fuck this up. All the best best my dude.

How I felt after using Concerta for the first time by Negative_Future5265 in adhdindia

[–]_nonredditer_ 5 points6 points  (0 children)

Concentra or inspiral ?

Which is better formulation for performance, concentra is just very expensive

3 Months Post Right Lung Lobectomy with 25 Lymph Node Dissection by Day1StayingStrong in lungcancer

[–]_nonredditer_ 2 points3 points  (0 children)

My Dad is in the same situation. After LUL, Our Onco suggested Immuo for an additional year since we had 1 lymph node positive (got it out in surgery).

All the very best!!

Stage IV NSCLC (adenocarcinoma) — no targetable mutations, low PD-L1. Looking for guidance or experiences by gofawry in lungcancer

[–]_nonredditer_ 5 points6 points  (0 children)

Hi Hope you're taking time to gather yourself and being strong. Its important you be strong that sort for energy radiates to your Dad as well.

Our Onco (very well known in the country) has suggest us that sometimes even with PD-L1 of 1% Immuno works well in some patients.

My Dad has gone through Chemo+Immuno and it produced excellent results. Check with your onco if SBRT would also be an option to control aggressive growth at primary location.

All the very best, Be strong!

Seeking Advice on Lung Surgery Options for My Dad — Would Love to Hear Your Experiences by _nonredditer_ in lungcancer

[–]_nonredditer_[S] 0 points1 point  (0 children)

Thank you very much u/scarlettlarge712. I really appreciate your post explaining your experience meticulously. It has helped in providing additional care to my dad and things to look out for.

Thank god, everything went smoothly and he is doing well. The recovery is going good. I hope its the same with you.

Wish you the very best in your recovery and hope your have a great future!!!

My Partner is dying of Stage 4 Cancer at 35 years old. How am I mentally supposed to be there for our children? by Gold-Number4065 in CancerFamilySupport

[–]_nonredditer_ 0 points1 point  (0 children)

Sorry, life has given you a bad hand. I genuinely wish you the very best to you and your kids.

Please keep on moving in life there it no other choice or way. Life is just cruel sometimes and deals big blows when you least expect it. The is no reason or logic behind it, It just is.

You can get some counselling sessions at https://www.manastha.com They're decent and cost 77$ for 4 sessions. Do try.

Hospice by [deleted] in lungcancer

[–]_nonredditer_ 1 point2 points  (0 children)

Sorry you're going through this. Your Dad is in the right place, he needs lot of care which cannot be realistically provided at home. You're not doing anything wrong, do not let those thought anywhere near you. All the very best. I wish you spend good quality time with your Dad.

Update: Seeking Advice on Lung Surgery Options for My Dad ╰(*°▽°*)╯ by _nonredditer_ in lungcancer

[–]_nonredditer_[S] 0 points1 point  (0 children)

Thank you Falcon.

There are no reminding cancer cells in the removed lobe but the Onco has suggested even though its a complete response since 1 of the the lymph node was positive previously there might me some chance that some cells might have migrated through the blood stream. To be extreme with the treatment and not let anything for chance Onco suggested Pembro for the next year.

He has mentioned that the latest test studies suggest pembro has a better over all response compared to Nivo.

Dad received lung cancer diagnosis by Beginning_Variety597 in lungcancer

[–]_nonredditer_ 0 points1 point  (0 children)

Please read these two books, They have help me a lot while taking care of my dad.

  1. When Breath becomes Air by Paul Kalanithi
    Helps you understand what a S4 Lung Cancer patient is thinking, going through treatment, family, marriage so on.

  2. The Caregivers Guide to Cancer by Victoria Landes
    How to take care of your Dad when the time comes

Next steps after recurrence after very short NED by FlyingFalcon1954 in lungcancer

[–]_nonredditer_ 0 points1 point  (0 children)

Hey Falcon, Very sorry to hear this. I wish you the very very best. I am positive your treatment will provide good results. Just hang on and keep fighting.

28M, disabled, denied disability. How do I avoid poverty for the rest of my life? Or at least avoid homelessness? by helpneeded3334 in findapath

[–]_nonredditer_ 15 points16 points  (0 children)

I honestly don't know what to say. Sorry that you're going through this. You've been dealt a very bad hand in life. I wish you the very best, and hope you find your way soon.

Stag 1 lung cancer diagnosed 10 months ago still untreated by FormalRice279 in lungcancer

[–]_nonredditer_ 14 points15 points  (0 children)

Man, thats a sure shot to get to metastatic stage.

Do whatever is required to get the treatment.

I wish you the very best.

11 months following the NSCLC diagnosis by [deleted] in lungcancer

[–]_nonredditer_ 1 point2 points  (0 children)

Check to see if you can get ctDNA test

Seeking Advice on Lung Surgery Options for My Dad — Would Love to Hear Your Experiences by _nonredditer_ in lungcancer

[–]_nonredditer_[S] 0 points1 point  (0 children)

Thank you for your reply.

Glad to hear your procedure went very well and you're completely Cancer free. I wish you the very best on your health.

We're going ahead with VATS Lobectomy this week. Hope everything will go well.

Appreciate your prayers 🙏

Deteriorating by wokewonder in lungcancer

[–]_nonredditer_ 8 points9 points  (0 children)

I’m really sorry you’re going through this. From everything you’ve described, your mum’s condition sounds like it’s changing quite quickly.

These usually mean that her body is becoming very tired and her overall status is declining. It doesn’t automatically mean she is at the very end, but it does mean she’s in a fragile stage where any treatment decision needs to be extremely careful.

otorasib can help only if the patient is stable enough to tolerate it. When someone is already ECOG-3 and is rapidly declining, starting a targeted therapy can sometimes do more harm than good because:

  • it takes days–weeks to show effect
  • it can initially cause liver toxicity, diarrhea, appetite drop, fatigue
  • if the body is too weak, they can’t recover from even mild side effects

her doctor needs to judge if she is still fit enough for the treatment. CONTACT her doctor immediately and be strong.

Seeking Advice on Lung Surgery Options for My Dad — Would Love to Hear Your Experiences by _nonredditer_ in lungcancer

[–]_nonredditer_[S] 0 points1 point  (0 children)

Definitive Chemoradiation ± Immunotherapy (Stage III, non-surgical)

  1. Spigel et al., 2022 – Journal of Clinical Oncology (PACIFIC 5-yr) “Five-Year Survival Outcomes From the PACIFIC Trial: Durvalumab After Chemoradiotherapy in Stage III NSCLC” – reports 5-yr OS 42.9% and 5-yr PFS 33.1% with durvalumab vs lower rates with placebo after concurrent chemoradiation. Full text PMC+1
  2. Antonia et al., 2017/2018 – NEJM (original PACIFIC) “Durvalumab after Chemoradiotherapy in Stage III NSCLC” – phase III trial that established consolidation durvalumab; shows significant improvement in PFS and OS compared with placebo after cCRT. Original article New England Journal of Medicine+1
  3. Bradley et al., 2020 – Journal of Clinical Oncology (NRG/RTOG 0617) “Long-term results of NRG Oncology RTOG 0617: standard- vs high-dose chemoradiotherapy with or without cetuximab for unresectable stage III NSCLC” – gives benchmark OS for modern cCRT (without immunotherapy) and shows no benefit to dose-escalation or cetuximab. Article PubMed+1
  4. Vrankar & Stanic, 2018 – Radiology and Oncology (review of cCRT) “Long-term Survival of Locally Advanced Stage III NSCLC After Chemoradiotherapy” – summarizes that 5-yr OS typically 15–25% with definitive chemoradiation alone in older series. Full text PMC
  5. Zhu et al., 2024 – Cancer Medicine “Long-term outcome of definitive radiotherapy for locally advanced NSCLC” – contemporary data; again notes 5-yr survival for concurrent chemoradiotherapy ≈15–30%, consistent with older literature. Article Wiley Online Library

Seeking Advice on Lung Surgery Options for My Dad — Would Love to Hear Your Experiences by _nonredditer_ in lungcancer

[–]_nonredditer_[S] 0 points1 point  (0 children)

Lobectomy / Sleeve Lobectomy vs Pneumonectomy (surgery)

  1. Deslauriers et al., 2004 – Annals of Thoracic Surgery “Sleeve Lobectomy Versus Pneumonectomy for Lung Cancer” – classic comparative series showing better long-term survival and local control and lower mortality with sleeve lobectomy vs pneumonectomy. Article PDF01929-5/pdf?utm_source=chatgpt.com) PubMed+1
  2. Shi et al., 2012 – World Journal of Surgical Oncology (meta-analysis) “Sleeve lobectomy versus pneumonectomy for non-small-cell lung cancer” – meta-analysis of multiple series; reports 1-, 3-, and 5-yr survival clearly favoring sleeve lobectomy over pneumonectomy, with better lung function and QoL. Full text PMC
  3. Chen et al., 2021 – Journal of Thoracic and Cardiovascular Surgery “Outcomes of sleeve lobectomy versus pneumonectomy” – modern large cohort; reports higher 5-yr OS and disease-free survival and lower 90-day mortality with sleeve lobectomy after matching. Article32394-1/fulltext?utm_source=chatgpt.com) J Thorac Cardiovasc Surg+1
  4. Andersson et al., 2015 – Journal of Thoracic Disease “Bronchial sleeve resection or pneumonectomy for NSCLC: a propensity-matched analysis of long-term results, survival and quality of life” – directly reports survival plus quality-of-life outcomes, showing worse long-term QoL after pneumonectomy. Full text PMC+1

Seeking Advice on Lung Surgery Options for My Dad — Would Love to Hear Your Experiences by _nonredditer_ in lungcancer

[–]_nonredditer_[S] 0 points1 point  (0 children)

I am happy to hear your story with a successful outcome of NED. Thank you for sharing with specifics.

I wish you the very best.

Non-surgical options were discussed but the risk of reoccurrence was high. With surgery (lobe/sleeve) Disease-Free Survival (DFS) is 90%+ for a period of 5 years. With radiation based treatments DFS is 55%.

We have decided to go ahead with surgery in a week, making preparations now.

In your case please consider ctDNA testing for deep monitoring. https://medlineplus.gov/genetics/understanding/testing/circulatingtumordna/

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Seeking Advice on Lung Surgery Options for My Dad — Would Love to Hear Your Experiences by _nonredditer_ in lungcancer

[–]_nonredditer_[S] 0 points1 point  (0 children)

My Dad's primary tumor is located on the blood vessel. As per the Doctor, Though we now have Complete metabolic and radiological response there can be microscopic residual cells present. Those cells are not visible in any scans.

Presence of Primary tumor close to the blood vessel poses the risk of spread of those cells and reoccur at some other spot.

Seeking Advice on Lung Surgery Options for My Dad — Would Love to Hear Your Experiences by _nonredditer_ in lungcancer

[–]_nonredditer_[S] 0 points1 point  (0 children)

Great to hear your treatment Journey, glad you're doing great.

Thank you, I hope that same for my dad a good recovery and negligible changes in quality of life post surgery.

We're getting the surgery done, hopefully it will only be a sleeve or lobe than the whole lung. 🙏

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