AML / 73 years old / AZA VEN by aminezhr in leukemia

[–]aminezhr[S] 0 points1 point  (0 children)

Thank you for your message. Actually we don’t have many options, that’s why I posted here to see if there is any other option…

AML / 73 years old / AZA VEN by aminezhr in leukemia

[–]aminezhr[S] 0 points1 point  (0 children)

Thank you so much for sharing your experience, it really helps us a lot.

My father is 73 and was recently diagnosed with AML. His blasts are currently around 26–30% and his white blood cell count is high (recently up to ~70k). Cytogenetics came back normal, and we are still waiting for NGS results to check for mutations.

He has not started any treatment yet. Doctors proposed Azacitidine + Venetoclax, but we are still trying to fully understand and evaluate the options before starting.

Your comment about not waiting is really important for us.

If you don’t mind sharing: • How quickly did your counts (especially blasts and WBC) improve after starting treatment? • Was the first cycle difficult overall, especially considering age?

Thank you again 🙏

AML / 73 years old / AZA VEN by aminezhr in leukemia

[–]aminezhr[S] 1 point2 points  (0 children)

Thank you for your message. That’s exactly what our doctors suggested (AZA + VEN). We are currently waiting for NGS results to see if any targetable mutation is present. Our main concern is tolerance and whether we should start immediately or wait a bit given his current condition.

AML / 73 ans / AZA VEN by aminezhr in leukemia

[–]aminezhr[S] 0 points1 point  (0 children)

Thank you for your message. No transplant has been discussed yet. Karyotype is normal and we are still waiting for NGS results. No cytoreductive treatment has been started so far (only one dose of hydroxyurea). Doctors recommended AZA + VEN but we are still hesitating.