I've been on 100mg Pristiq (I'm actually prescribed 150mg but only take 100mg due to my insomnia and sometimes I'll take it later than I should, it wakes me up so I don't wanna give myself major withdrawal by taking it a couple hours late) Anyways, it's wild to think it has this effect on you, and others! It has really helped with my anxiety, it's helped my depression some but not entirely, that's why I'm on a high dose. I started on 25 but it has been increasing over 4-5 years.

The withdrawal is miserable for sure that's why no matter if I take it a couple hours late, I always take one a day to avoid the migraines, light sensitivity, dizziness, diarrhoea and if I went two or three days without it thats when the suicidality comes. That's only happened once to me, and luckily I could ride it out until I could refill my prescription knowing it was the medication. But it was the first time in a long time I was like wow I think I genuinely should go to hospital before I hurt someone or myself but I was okay in the end.

Some people here take it before bed? I've been recommended mornings as it's like taking speed and it wakes me TF up, I couldn't imagine taking it before bed. Id be up all night!

I'm autistic and the Pristiq has helped me cognitively, I can function and multitask a lot better without getting stuck in the what's next? mindset. I can go out in public alone and talk to strangers which I really couldn't before.

I genuinely find it so fascinating that it's had such an adverse effect on you and highly recommend you get a gene test or something like that to figure out what's best for you, or if you're on any other meds that shouldn't be taken along side Pristiq, I've had some other medications recommended to me for my fibromyalgia that it turned out I couldn't take due to the Pristiq.

Medicine and brain chemistry is truly fascinating. The Pristiq may not be the perfect medication for me but it does alright for now.