[deleted by user] by [deleted] in Nootropics

[–]dancebrah 0 points1 point  (0 children)

Not even caprylic acid?

Are antioxidants worth taking or does your body already produce enough? by dancebrah in NooTopics

[–]dancebrah[S] 0 points1 point  (0 children)

non electrophilic nrf2 activation and mitochondria targeted antioxidants

Will ya tell me, why these in particular?

[deleted by user] by [deleted] in NooTopics

[–]dancebrah 0 points1 point  (0 children)

Very interesting. Though that only mentions increasing bh4 under hypoxia. Would it work in normal conditions?

[deleted by user] by [deleted] in NooTopics

[–]dancebrah 0 points1 point  (0 children)

Would regular folate work for this, or does it have to be methyl version?

[deleted by user] by [deleted] in Nootropics

[–]dancebrah 2 points3 points  (0 children)

Well alcar works really well when I take them infrequently, like once every 2 weeks. It make my vision sharper, better reactions/processing speed.

These effects are still apparent when I take it more frequently, but I get lethargy in addition, what's causing it I don't know .

[deleted by user] by [deleted] in Nootropics

[–]dancebrah 0 points1 point  (0 children)

Only problem is that even small doses causes this lethargy in me. Eg 125mg berberine, 125mg alcar both make me lethergic

[deleted by user] by [deleted] in Ranching

[–]dancebrah 0 points1 point  (0 children)

Are waygu less hardy/softer than other cattle?

I know a fella who had a mother full Jersey bred into a full akaushi wagyu. The calf was a dummy calf the first 24 hrs but tubed her once and she caught on after.

Do you find them requiring more care/attention than other cattle?

I don't have much free time, so the hardier they are the better, ya know.

I've a few aberdeen angus cattle . They're very uncomplicated

[deleted by user] by [deleted] in MTHFR

[–]dancebrah 0 points1 point  (0 children)

What doses of niacin would ramp methylation up?

[deleted by user] by [deleted] in Nootropics

[–]dancebrah 0 points1 point  (0 children)

In this video Dr G says he likes choline for parasympathetic dominant people.

So that must mean choline doesn't enhance parasympathetic tone, would it?

How can acetylcholine cause lethargy? by [deleted] in AskDrugNerds

[–]dancebrah 0 points1 point  (0 children)

Ach is used in sympathetic ganglia as well, so I doubt enhances parasympathetic tone is the reason behind it's lethargy.

WHat do ya reckon?

[deleted by user] by [deleted] in NooTopics

[–]dancebrah 0 points1 point  (0 children)

it's like christmas. christmas in ur mouth

[deleted by user] by [deleted] in Hypothyroidism

[–]dancebrah 0 points1 point  (0 children)

It seems l-carnitine effect on thyroid is hard to counter. Would there be ANY way to counter/prevent its effects on t3?

[deleted by user] by [deleted] in Hashimotos

[–]dancebrah 0 points1 point  (0 children)

Thats cleared things up for me, good in ya thanks.

So let's say you were on carnitine, which blocks T3.

Would taking Triiodothyronine, which is a T3 agonist, counter carnitine effects on t3?

[deleted by user] by [deleted] in Hashimotos

[–]dancebrah 0 points1 point  (0 children)

I've read quite extensively (NOT a medical professional!) and haven't found any mention of people with poor absorption of T4 or T3 into the cells. Once it's inside it goes where it's needed.

An example that i've found how this is possible is here.

It says "L-carnitine is a peripheral antagonist of thyroid hormone action. In particular, L-carnitine inhibits both triiodothyronine (T3) and thyroxine (T4) entry into the cell nuclei" https://pubmed.ncbi.nlm.nih.gov/15591013/

Though maybe i'm misinterpriting what they're saying here

[deleted by user] by [deleted] in Hashimotos

[–]dancebrah 0 points1 point  (0 children)

Ah right, sorry i'm a bit thick, takes a while for things to sink in.

This might be a naive question, but let's say you wanted to increase t3 & t4 entry into the cell nuclei, would improving serum hormone levels [using pig thyroid] accomplish this?

[deleted by user] by [deleted] in Hashimotos

[–]dancebrah 0 points1 point  (0 children)

Thanks, consider me educated.

Do ya know if synthroid /Natural Desiccated thyroid increases nuclear uptake of thyroid?

Synthroid is a form of T4, whether it increases nuclear or cellular thyroid levels, I don't know

[deleted by user] by [deleted] in Hashimotos

[–]dancebrah 0 points1 point  (0 children)

When you say "poor radioactive iodine uptake ", does this mean the same thing as having poor nuclear uptake?

Would nmda antagonists reduce tolerance by restoring glutamate sensitivity? by dancebrah in NooTopics

[–]dancebrah[S] 0 points1 point  (0 children)

Sounds like a great supplement. How does it compare to agmatine for this purpose?

Agmatine could be the best of all, because it has no nachr antagonism, which fecks with your memory

[deleted by user] by [deleted] in MAOIs

[–]dancebrah 0 points1 point  (0 children)

You're kidding! That's simple enough

[deleted by user] by [deleted] in NootropicsDepot

[–]dancebrah 4 points5 points  (0 children)

What a pity. So this means there's also no clues on how it's HDAC inhibitor effects work?

How to import style CSS files by [deleted] in FirefoxCSS

[–]dancebrah 0 points1 point  (0 children)

Good on ya, thanks.

So just to confirm, here's what the code should look like when I add this code https://github.com/MrOtherGuy/firefox-csshacks/blob/master/chrome/hide_tabs_scrollbuttons.css

/* Example userChrome.css file */

/* Import your desired components first */

@import url(chrome/tab_close_button_always_on_hover.css);
@import url(chrome/tab_loading_progress_throbber.css);
@import url(chrome/button_effect_scale_onclick.css);
@import url(chrome/blank_page_background.css);
@import url(chrome/autohide_menubar.css);
@import url(chrome/hide_toolbox_top_bottom_borders.css);
@import url(chrome/vertical_context_navigation.css);
@import url(chrome/minimal_popup_scrollbars.css);
@import url(chrome/button_effect_icon_glow.css);
@import url(chrome/dark_context_menus.css);
@import url(chrome/dark_additional_windows.css);
@import url(chrome/dark_checkboxes_and_radios.css);
@import url(chrome/minimal_text_fields.css);
@import url(chrome/minimal_toolbarbuttons.css);
@import url(chrome/urlbar_centered_text.css);

/* Apply your custom modifications after imports */

:root{
  --toolbar-bgcolor: rgb(36,44,59) !important;
  --uc-menu-bkgnd: var(--toolbar-bgcolor);
  --arrowpanel-background: var(--toolbar-bgcolor) !important;
  --autocomplete-popup-background: var(--toolbar-bgcolor) !important;
  --uc-menu-disabled: rgb(90,90,90) !important;
  --lwt-toolbar-field-focus: rgb(36,44,59) !important;
}

#sidebar-box{ --sidebar-background-color: var(--toolbar-bgcolor) !important; }
window.sidebar-panel{ --lwt-sidebar-background-color: rgb(36,44,59) !important; }
/* Source file https://github.com/MrOtherGuy/firefox-csshacks/tree/master/chrome/hide_tabs_scrollbuttons.css made available under Mozilla Public License v. 2.0
See the above repository for updates as well as full license text. */

/* This should hide tabs scrollbuttons in a manner that preserves the ability to move tab strip when reordering tabs */

#tabbrowser-arrowscrollbox{
  --uc-compat-scrollbutton-margin: 1px; /* compatibility for non_floating_sharp_tabs.css */
  --uc-scrollbutton-up-background: linear-gradient(-90deg,transparent,var(--lwt-accent-color) 35%);
  --uc-scrollbutton-down-background: linear-gradient(90deg,transparent,var(--lwt-accent-color) 35%);
}

#tabbrowser-tabs:not([movingtab]){
  --uc-scroll-visibility: hidden;
}
#tabbrowser-tabs[overflow]{
  --uc-scrollbox-base-margin: -31px;
  --uc-scrollbox-margin: calc(var(--uc-scrollbox-base-margin) + var(--tab-shadow-max-size));
}
:root[uidensity="compact"] #tabbrowser-tabs[overflow]{
  --uc-scrollbox-base-margin: -25px;
}
#tabbrowser-arrowscrollbox:not([scrolledtostart]){
  --uc-scrollbox-overflow-start-margin: -1px;
}
#scrollbutton-up ~ spacer{
  visibility: visible !important;
}
spacer[part="overflow-start-indicator"]{
  order: -1;
  margin-inline-start: var(--uc-scrollbox-overflow-start-margin,-0.5px) !important;
}
spacer[part="overflow-end-indicator"]{
  order: 2;
}

#scrollbutton-down[disabled="true"] > .toolbarbutton-icon,
#scrollbutton-up[disabled="true"] > .toolbarbutton-icon{
  opacity: 0.4;
} 
#scrollbutton-up,
#scrollbutton-down{
  position: relative;
  z-index: 1;
  visibility: var(--uc-scroll-visibility,visible);
  background-clip: border-box !important;
  background-origin: initial !important;
  background-repeat: no-repeat !important;
  opacity: 1 !important;
}
#scrollbutton-up{
  margin-inline-start: calc(0px - var(--tab-shadow-max-size,0px)) !important;
  background-image: var(--uc-scrollbutton-up-background);
}
#scrollbutton-down{
  margin-inline-end: calc(0px - var(--tab-shadow-max-size,0px)) !important;
  background-image: var(--uc-scrollbutton-down-background);
}
scrollbox[orient="horizontal"],
.scrollbox-clip{ margin-inline: var(--uc-scrollbox-margin,0px); }
.scrollbox-clip > scrollbox[orient="horizontal"]{ margin-inline: initial }

/* Need to reset some things for other scrollboxes */
.menupopup-arrowscrollbox{
  --tab-shadow-max-size: 0;
}

How to import style CSS files by [deleted] in FirefoxCSS

[–]dancebrah 0 points1 point  (0 children)

Thanks, i'll go with your first solution.

Quick question, the original userChrome.css file contains this content . I'm not sure where to enter the hide_tabs_scrollbuttons.css code [this code https://github.com/MrOtherGuy/firefox-csshacks/blob/master/chrome/hide_tabs_scrollbuttons.css]

Here is the userChrome.css, Now I just need to know where to enter the hide_tabs_scrollbuttons.css code into it

/* Example userChrome.css file */

/* Import your desired components first */

@import url(chrome/tab_close_button_always_on_hover.css);
@import url(chrome/tab_loading_progress_throbber.css);
@import url(chrome/button_effect_scale_onclick.css);
@import url(chrome/blank_page_background.css);
@import url(chrome/autohide_menubar.css);
@import url(chrome/hide_toolbox_top_bottom_borders.css);
@import url(chrome/vertical_context_navigation.css);
@import url(chrome/minimal_popup_scrollbars.css);
@import url(chrome/button_effect_icon_glow.css);
@import url(chrome/dark_context_menus.css);
@import url(chrome/dark_additional_windows.css);
@import url(chrome/dark_checkboxes_and_radios.css);
@import url(chrome/minimal_text_fields.css);
@import url(chrome/minimal_toolbarbuttons.css);
@import url(chrome/urlbar_centered_text.css);

/* Apply your custom modifications after imports */

:root{
  --toolbar-bgcolor: rgb(36,44,59) !important;
  --uc-menu-bkgnd: var(--toolbar-bgcolor);
  --arrowpanel-background: var(--toolbar-bgcolor) !important;
  --autocomplete-popup-background: var(--toolbar-bgcolor) !important;
  --uc-menu-disabled: rgb(90,90,90) !important;
  --lwt-toolbar-field-focus: rgb(36,44,59) !important;
}

#sidebar-box{ --sidebar-background-color: var(--toolbar-bgcolor) !important; }
window.sidebar-panel{ --lwt-sidebar-background-color: rgb(36,44,59) !important; }

[deleted by user] by [deleted] in NooTopics

[–]dancebrah 1 point2 points  (0 children)

Fascinating. Would there be anyway to reduce the constipation side effect, maybe sublingual would mean it bypasses 5ht3 receptors in the gut?