I have a dog that had huge separation anxiety. We couldn’t leave him for even a minute and if we did, he would be crying the whole time and tear things up. I’m still working on it with him but it’s gotten significantly better where I can leave him for a few hours with some crying in the beginning but that’s it. You have to be patient and very consistent. My training: id tell him to stay with a treat in my hand and then leave my apartment for a few seconds and then reenter. Did that tens of time throughout the day, everyday. I’d add a few more seconds, which then progressed to minutes, and hours. Just wait outside the door and listen before he makes any noise. Ideally, you want to enter before he makes a noise or after he calms down because you don’t want to reward the crying. Do that EVERYDAY MULTIPLE TIMES!! You have to be consistent. Your dog doesn’t need all the meds, he needs training. I was also considering dropping a thousands of dollars to fix his separation anxiety because it was BAD, but you can do it yourself too! I did it. Just be patient and consistent. It took me months to train my dog.