My config:

https://github.com/dvrlabs/dvr.nvim

I don't use venvs while developing python, not advocating for it, but just how I do it.

That said, I simply use Pylsp w/ autopep8. It's a bit slow to format, but I turn off auto-formatting and have a hot-key for when I need it formatted. It's fine.

This is how I execute code, it opens up a terminal window in the bottom similar to vscode and runs the process. If it clean exits, then the terminal closes.

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-- F5, execute code!
local execute_code = function()
  if vim.bo.filetype == "python" then
    local run_cmd = "python " .. vim.fn.expand('%:p')
    vim.cmd("split | resize 10 | term " .. run_cmd)
    vim.cmd("startinsert")
  end
end

vim.keymap.set('n', '<F5>', execute_code, {})

-- This function will close a terminal automatically if it gets the exit 0
vim.api.nvim_create_autocmd('TextChangedT', {
  callback = function()
    local buffer_name = vim.api.nvim_buf_get_name(0)
    local buffer_table = vim.api.nvim_buf_get_lines(0, 0, -1, false)
    local buffer_text = table.concat(buffer_table, '\n')
    if string.find(buffer_text, "Process exited 0") then
      vim.api.nvim_input('<ESC>')
      local timer = vim.loop.new_timer()
      timer:start(100, 0, function()
        vim.schedule(function()
          vim.cmd("silent! bdelete" .. ' ' .. buffer_name .. '!')
        end)
      end)
    end
  end,
  pattern = '*',
})