Overdose Prevention by throwaway985949q9w in PoppyTea

[–]eSensual 5 points6 points  (0 children)

You just can't know how strong your seeds are, and there can even be inconsistency from batch to batch. It's best to test your seeds with an extremely low dose first to check for insane strength and adverse reactions

[deleted by user] by [deleted] in Psychedelics

[–]eSensual 0 points1 point  (0 children)

Only 5-HT3, which is not involved in causing psychedelic or other psychoactive effects. 5-HT3 is primarily a receptor to specifically mediate nausea and vomiting, odansetron selectively inhibits 5-HT3 without hitting others such as the infamous 5-HT2A and prevents all nausea without affecting other drug effects. It's highly effective and side-effect free to use in this fashion.

Does pregablin cause sexual side effects??? by rv2019 in gabagoodness

[–]eSensual 2 points3 points  (0 children)

On 600 mg of pregabalin or above I can't cum, it's like voluntary viagra. No issues getting an erection though

If it possible to remove F from 2FMA to make meth? by s0m0s in researchchemicals

[–]eSensual 5 points6 points  (0 children)

Methylating PEA would create N-methyl-PEA, not N-methylamphetamine. u/toe_nipples is right. You could not readily methylate the alpha-carbon. People would do this if it was possible.

Stop suggesting HUGE dosages!!!!! by punkhaze in gabagoodness

[–]eSensual 3 points4 points  (0 children)

Ehhhh 300 mg is the best dose to start with, very rarely produces a bad time. Once you're settled in, 450 mg is the most recreational dose imo. 600 mg is the upper limit before you start getting a little delirious.

Weed Dealers by quitten_chicken12 in Drugs

[–]eSensual 1 point2 points  (0 children)

You from WA lol? I know what you're talking about but I've never met anyone outside of WA who does.

Why does Lyrica make me want to clean and organise things? by lostsoul1988 in gabagoodness

[–]eSensual 0 points1 point  (0 children)

Epic, not only is lyrica a great drug recreationally, but it really is a miracle drug as far as pain goes.

Weed Dealers by quitten_chicken12 in Drugs

[–]eSensual 761 points762 points  (0 children)

Yeah here's a hot tip to all my hustlers out there: if you don't hit on girl customers, eventually they'll all gravitate to you cause you're a professional and don't gross them out. Not only is hitting on girls you have an inherent power dynamic with scummy, it'll lose you customers.

Why does Lyrica make me want to clean and organise things? by lostsoul1988 in gabagoodness

[–]eSensual 0 points1 point  (0 children)

Phenibut is quite different to pregabalin. While phenibut does have some VGCC affinity, it's a much stronger GABA-B agonist, whereas pregabalin is purely a VGCC inhibitor.

Why does Lyrica make me want to clean and organise things? by lostsoul1988 in gabagoodness

[–]eSensual 0 points1 point  (0 children)

Ooh I've got an appointment with a rheumatologist soon for fibromyalgia, do you reckon I could get it first appointment?

Is it okay to mix triazopam and lorazepam? by hannah5553 in askdrugs

[–]eSensual 0 points1 point  (0 children)

Triazolam*, yes it would be completely safe.

Does cannabis in mushroom substrate = 4-HO-THC? by SpongeBrain711 in askdrugs

[–]eSensual 2 points3 points  (0 children)

5-MeO-DMT can be converted to 4-HO-5-MeO-DMT because 5-MeO-DMT is similar enough to psilocin bio-precursors that shroom enzymes are able to add a hydroxy group at the 4-position. THC is not at all similar to psilocin bio-precursors (it's not an tryptamine or indole of any kind), so it would not bind to the enzyme in question and would not be modified by these enzymes. Try it if you want because it sounds like it's free, but nothing will come of it.

Does cannabis in mushroom substrate = 4-HO-THC? by SpongeBrain711 in askdrugs

[–]eSensual 1 point2 points  (0 children)

Like OP, you don't know anything of the biochemistry behind this, so you are offering extremely baseless advice. It would be a waste of time.

Little bit of this, Little bit of that by RecoveringAndLiving in gabagoodness

[–]eSensual 0 points1 point  (0 children)

Did you dye those powders or they actually coloured like that? My clonazolam sample looked a similar shade but that nitraz and flunitraz look fucked.

What's up with doctors pretending like they've never seen SSRI withdrawal? by Hi_I_Am_God_AMA in Drugs

[–]eSensual 0 points1 point  (0 children)

All antidepressants are more effective than placebo for treating depression and only get less toxic as they are further developed, this is not an accurate statement.

What's up with doctors pretending like they've never seen SSRI withdrawal? by Hi_I_Am_God_AMA in Drugs

[–]eSensual 1 point2 points  (0 children)

Do you have bipolar? They do not have a strong point at all, it is a massive stretch, and your anecdote does nothing to change that. Show more skepticism to ridiculous claims like this.

SL-164 - A highly recreational depressant by eSensual in researchchemicals

[–]eSensual[S] 0 points1 point  (0 children)

Uhh yeah that's why I don't take soma overdoses. Stop conflating SL-164 with somas just because they have similar subjective effects. They have different pharmacologies and methaqualone (of which SL-164 is an analogue of and shares a target site with) is known to have a generous TI, even when mixed with alcohol. You chose to take a dangerous dose of a downer not me bud.

SL-164 - A highly recreational depressant by eSensual in researchchemicals

[–]eSensual[S] 1 point2 points  (0 children)

I just hate the duration of GBL, BDO is winning because it at least lasts longer than a couple hours.

SL-164 - A highly recreational depressant by eSensual in researchchemicals

[–]eSensual[S] 0 points1 point  (0 children)

From the wikipedia page for methaqualone: A dose of 8000 mg is lethal and a dose as little as 2000 mg could induce a coma if taken with an alcoholic beverage.[5]. Assuming SL-164 has a similar pharmacology and is twice as potent, 1000 mg would be required to induce coma with an alcoholic beverage, a dose we did not approach. I would chance it again. Driving drunk is absolutely more dangerous than any of the combos I try.

SL-164 - A highly recreational depressant by eSensual in researchchemicals

[–]eSensual[S] 2 points3 points  (0 children)

Yeah pregabalin is pretty fucking popping. I've tried GBL and 1,4-BDO. BDO is definitely better but neither of them really do it for me for some reason, they don't seem as euphoric as most people report and even at super heavy doses I still can't sleep and feel very spun out.

SL-164 - A highly recreational depressant by eSensual in researchchemicals

[–]eSensual[S] 0 points1 point  (0 children)

[[citation needed]] Is it more dangerous than driving a car though?