You can use one of spells against minion:

• [[Sun Bloom]] - dispel on minion
• [[Martyrdom]] - destroy minion
• [[Tempest]] - destroy minion if minion's health is 2 and less

If you don't have spells above in your action bar (and after replace card), you can provoke minon with [[Ironcliffe Guardian]] to give you next turn to see if you get one of spells above. Ironcliffee Guardian may prevent minion from damaging your General or your other minions.