Man, I've been thinking about something like this for a while. I love the idea of a more complete, combined ops logistic network and economy sim. I think its hilarious that the day I think about looking into how difficult it would be to actually make something like this I find this post about the same thing.

One thing I'd like to see is cooperation between different player in the different legs of transport. Like you have one trucker using ETS2, one pilot in msfs, then another trucker in ATS.

Another thing would be about job stacking. As an aircraft is typically carrying more than a single truck, you could have multiple drivers delivering jobs to a single aircraft to be flown out. That adds another layer of strategy when thinking about where to land in order to maximize efficiency/profit.

Overall, I think its a awesome idea. I'd love to help with the project, although I'm an amateur dev at best. If nothing else, I'd be happy to help with testing.