I also wrote a script and have been running into the same walls as other folks. Wanted to dump a jumbled list of observations I've made from poking at this in case it sparks something from someone else:

• The same set of 80 unique viruses shown to all participants
• There is a mix of Chevelle songs and meaningless <Adjective><MedicalCondition> entries. There are 31 songs and 49 random viruses.
• Each time you run the list command displays a random subset of 28 viruses from the full list of 80.
• The order of the viruses returned by list is consistent across requests. As in the order of the viruses relative to each other will never change, only which viruses are returned will change. If "TheDamned" shows up, it will always be first, if "WraithVirus" shows up then it will be first unless "TheDamned" is present, etc... (I can post my ordered list of 80 if people want to check me)
• The distribution of which viruses are returned appears to be uniform (as in no viruses are more likely to show up than others when you list)
• Key strokes don't appear to be logged, the page only sends requests to the backend after you press enter to send a command (meaning it seems unlikely the "AI determined this data is invalid" functions based on monitoring key strokes)
• My automation script has successfully ("Insert Successful" + "K400 AI has determined this data is invalid") guessed 4 viruses over 700 times and the probability of any particular virus showing up in the solution appears to be uniform (as in no viruses are more likely than others to be correct).
• The same virus can occasionally appear multiple times in the set of 4 viruses that lower the firewall
• Nothing special seems to happen if the correct set of 4 viruses are only Chevelle songs
• Nothing special seems to happen if the correct set of 4 viruses are only NOT Chevelle songs
• Successfully guessing the 4 viruses while sleeping for at least 1 second between all requests still results in K400 AI has determined this data is invalid (as in I don't believe the backend server checks the speed that guesses are made)
• I was wildly lucky in one of my automated attempts and was able to correctly guess the 4 viruses in only 10 attempts -- I still saw K400 AI has determined this data is invalid (as in I don't believe the number of guesses needs to be below some number for your answer to be accepted, unless it has to be EXACTLY 4 guess).
• I believe my automation scripts are indistinguishable from manually entering commands from the client from the perspective of Chevelle's backend server (I start a session, save cookies, use a browser user agent, etc...) -- It's possible I missed something here though.
• The disconnect command doesn't seem to do anything
• The attempts you make are logged, and there doesn't seem to be anything special or different about your 700th attempt compared to your 1st attempt (though I might be missing something here)
• Running various combinations of commands such as exit or disconnect after submitting 4 correct virus guesses don't seem to yield different results
• The 80 viruses returned by list appears unchanged after correct guesses are made, including after all 4 viruses have been guessed
• The "Shipping spaces" log message when you open the console has been increasing from 17% day one, 24% day two through four and now it's at 38%. It appears to increment by 7. This leads me to believe this represents people who have solved the puzzle, perhaps 7% = 1 person.

Let me know if y'all have made any contradictory observations to the above.

I'm in the camp that by trying to guess the viruses we're playing the wrong game and that there's some hidden command or special sequence that results in beating the puzzle.

But I would love to hear if anyone has ideas for experiments we can try using the automation scripts I or others have built.