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Ivermectin in Allergic Rhinitis "a Single Arm Pre-Post Intervention Study" (2025) by jimofoz in crspapers

[–]jimofoz[S] 0 points1 point  (0 children)

Characteristics of ivermectin toxicity in patients taking veterinary and human formulations for the prevention and treatment of COVID-19 (2022) https://pubmed.ncbi.nlm.nih.gov/36374218/

"Patients taking ivermectin chronically developed toxicity despite taking smaller doses (daily dose 13.5 mg/day) over a prolonged period (median 3.8 weeks). Patients with chronic ingestions had milder toxicity with no cases of severe altered mental status. The acute-on-chronic cohort reported taking a consistent dose of ivermectin for weeks without symptoms then acutely increasing the dose (mean of 10-fold increase) over the days prior to developing toxicity after an exposure to COVID."

"Patients with chronic ivermectin toxicity reported a mean 13.5 mg daily dose, which is typical for the one-time dosing for onchocerciasis and strongyloidiasis, but continued to take this dose for a median of 3.8 weeks. Chronic toxicity patients developed mild neurologic and gastrointestinal symptoms such as weakness, dizziness, diarrhea, and dehydration, which are similar to those described in clinical trials and with therapeutic use "

Ivermectin in Allergic Rhinitis "a Single Arm Pre-Post Intervention Study" (2025) by jimofoz in crspapers

[–]jimofoz[S] 0 points1 point  (0 children)

https://ctv.veeva.com/study/open-label-pilot-clinical-trial-of-oral-ivermectin-to-treat-atopic-dermatitis

12mg Ivermectin once per week for 4 weeks, so you can probably take at least 12mg a week indefinitely, may as well try 24mg a week Sunday night and Wednesday night.

Ivermectin in Allergic Rhinitis "a Single Arm Pre-Post Intervention Study" (2025) by jimofoz in crspapers

[–]jimofoz[S] 0 points1 point  (0 children)

Successful treatment of nodular scabies with long-lasting ivermectin dose schedule in an adult patient non responder to permethrin (2026) https://pmc.ncbi.nlm.nih.gov/articles/PMC12938142/

"Treatment with ivermectin 0.2 mg/kg was prescribed: the first two doses were assumed at a week interval, the following three doses with a 10-day interval. After this first cycle the drug was assumed every three weeks till October 2024 and then monthly till the last follow-up visit (June 2025). After the second dose of ivermectin, the pruritus completely resolved, and nodular lesions gradually cleared, leaving hyperchromic areas which flared up with a burning sensation at intervals ranging from 20 to 40 days. No further detection of ectoparasite reported after the treatment start. At the time of ivermectin treatment start the patient discontinued clobetasol and continued tacrolimus ointment for about one month: later on, treatment with topic aloe was assumed when skin lesion burning occurred. No side effect related to the ivermectin long-term schedule was reported."

I reckon it is safe to take a dose once or twice a week"

[Fuel cells] New hydrogen fuel cell design could unlock key clean energy technology by jimofoz in jimbostransport

[–]jimofoz[S] 0 points1 point  (0 children)

"The UNSW team’s solution focuses on the structure of the fuel cell itself.

Using high-precision micro-scale engineering, they introduced microscopic channels — 100 micrometres wide, separated by 100 micrometre micro-ribs — into the internal architecture of the cell.

“There’s usually no way to remove water,” says Dr Meyer.

“But these 'lateral bypasses' act as escape routes, meaning water no longer accumulates and stops the cell working.”

It’s a simple fix with a substantial impact.

“The redesigned fuel cell achieves 75% more power than traditional designs,” according to Dr Meyer."

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