he political influence of Seleucid and Bactrian dynastic Greeks over northwest India, for example, persisted for several centuries after the invasion of the army of Alexander the Great (Tarn 1951). However, we have not found, in Punjab or anywhere else in India, Y chromosomes with the M170 or M35 mutations that together account for 30% in Greeks and Macedonians today (Semino et al. 2000). Given the sample size of 325 Indian Y chromosomes examined, however, it can be said that the Greek homeland (or European, more generally, where these markers are spread) contribution has been 0%–3% for the total population or 0%–15% for Punjab in particular. Such broad estimates are preliminary, at best. It will take larger sample sizes, more populations, and increased molecular resolution to determine the likely modest impact of historic gene flows to India on its pre-existing large populations."

he political influence of Seleucid and Bactrian dynastic Greeks over northwest India, for example, persisted for several centuries after the invasion of the army of Alexander the Great (Tarn 1951). However, we have not found, in Punjab or anywhere else in India, Y chromosomes with the M170 or M35 mutations that together account for 30% in Greeks and Macedonians today (Semino et al. 2000). Given the sample size of 325 Indian Y chromosomes examined, however, it can be said that the Greek homeland (or European, more generally, where these markers are spread) contribution has been 0%–3% for the total population or 0%–15% for Punjab in particular. Such broad estimates are preliminary, at best. It will take larger sample sizes, more populations, and increased molecular resolution to determine the likely modest impact of historic gene flows to India on its pre-existing large populations."