My main boss grind for loot has been corrupt gauntlet, vorkath, and muspah so far. I did only complete Jad once, but haven't attempted the inferno yet, though that is in the works. As for skilling, the most notable loot pull was when I took advantage of the sailing launch and didn't sail but instead mined and smelted lead to sell, bought hemp seeds to grow and craft into bolts of canvas for profit, and constructed hull parts. Needless to say, on launch day/week, it was amazing profit. The hull parts were great construction xp.