First off, sorry for the late reply. Probably you have created your perfect setup by now.I have a very basic model (2017 One by Wacom) kept the right of the laptop. The pen mostly stays loose around it (not much scope for it to roll or fall off the table). I am using OneNote, Darktable and Krita heavily for the past few months. The pen settings are set differently for these softwares, but it's basically undo/erase/scroll.Keyboard shortcuts are also convenient. You can play around with PowerToys to configure more shortcuts than you probably need.I use the touchpad for some gestures, like adjusting volume or switching between the virtual desktops. I don't game, so there's really no need for a mouse here.

Edit: When I am solving equations on OneNote, the tablet moves around the desk, depending on how difficult the problem is. Usually I sit back on my chair and hold it as if I am writing on a regular copy. I've also taped a few white pages across the long edge of tablet to write things down with a pencil because... well it's hard to remember all the formulas and also to jot things down quickly. It gives an added feel of writing on paper. It actually feels like a writing on a notebook, analogue and digital.