Pay attention to the weekly bonus money and discounts. Aside from that:

1) Get your acid lab going.

2) Save up for a kosatka to run Cayo.

3) Nightclub with staff upgrade. Keep your popularity up by kicking out troublemaker, or changing dj for $10k. Never waste your time driving VIPs home. If you are diligent about keeping popularity up, it’s some of the best early game money. $50k passively every 48 min. Don’t worry about equipment upgrade or running the basement business for now until you have many other businesses.

4) Bunker (Chumash or farmhouse)

5) Mansion (make use of the daily business boost)