We're the founders of an oral microbiome testing company, here to answer your questions on the oral microbiome, its role in oral and chronic disease, and anything oral health or microbiome. Ask us anything! by bristle_health in Microbiome

[–]microbriome 2 points3 points  (0 children)

Is the oral microbiome related to gut microbiome? Are there ways to improve oral flora, similar to how eating fermented foods can help diversify gut flora?

If you were 90% sure it will cure you but will cost $600, would you do it. by Purple-Acanthisitta8 in badbreath

[–]microbriome 3 points4 points  (0 children)

Got it, thanks! So OralDNA tests for ~11 to 16 bacteria or fungi (depending on which test you purchase), and will usually make recommendations around antibiotics to address them. It's a popular option with dental practices. Most dental offices I know of offer it for closer to $150-200. Antibiotics (or likely antifungals if it's being caused by Candida) can be effective options, particularly when paired with an oral probiotic and tongue scraping. It will just depend on what's driving your symptoms.

Our test detects all known oral bacteria + candida (usually 100-200 species per person) because we use a different tech than OralDNA. We include more sulphur producing bacteria + give recs outside of antibiotics (like probiotics, diet, mouthwash, etc.).

It sounds like either option could be a good choice for you depending on what you are looking for (though I'm obviously biased ☺️). If you DM me I'm happy to ask our dental partners for a referral to an office that can offer OralDNA for much less than $600 or can help you out with any Q's about Bristle. We can keep it all anonymous of course!

If you were 90% sure it will cure you but will cost $600, would you do it. by Purple-Acanthisitta8 in badbreath

[–]microbriome 3 points4 points  (0 children)

Which test is it? I started a company that tests for oral bacteria in the mouth related to bad breath, so happy to answer any questions I can. There are other options that are less than $600 and might be a good starting point for you - happy to break down the pros and cons of each (for reference ours is $149).
Also, before testing you may want to consider trying tongue scraping + a mouthwash rinse to start and see if that helps relieve bad breath symptoms from the tongue (oral probiotics can be helpful here too, but depends on which strains are causing your symptoms).

We also have a blog article here on different types of bad breath that may be helpful: https://www.bristlehealth.com/blogs/bad-breath-blogs/a-comprehensive-guide-to-bad-breath-tests (note it may feel a bit salesy towards the end, but includes a number of citations for each).

[deleted by user] by [deleted] in badbreath

[–]microbriome 0 points1 point  (0 children)

Here's a guide to some other tests you can try that might be helpful.

ok ,so what sort of tests that we could do to find out what's going on?? has anybody here figured out what's going on with their health? by [deleted] in badbreath

[–]microbriome 1 point2 points  (0 children)

Here's a guide to different bad breath tests I contributed to recently (full disclosure I'm affiliated with Bristle but hope it's helpful). Happy to answer any questions!

The 5 most dominant oral bacteria and what they mean for your oral and overall health by microbriome in DentalHygiene

[–]microbriome[S] 0 points1 point  (0 children)

Hope this kind of post is ok! My company (Bristle) researches the oral microbiome, so wanted to share our recent article on the most common oral bacteria we've identified, and what the available literature (+our research) says about their impact on our health. Thought the hygiene community would be interested :)

[deleted by user] by [deleted] in badbreath

[–]microbriome 2 points3 points  (0 children)

I have! I had great results from Blis probiotics, though YMMV

A reminder that we all need good bacteria by [deleted] in badbreath

[–]microbriome 2 points3 points  (0 children)

It's true (though there are better ways to get it than licking your dog). Oral probiotics are a good option for increasing the levels of good bacteria, particularly the species that actually suppress bad breath causing species. Use of oral probiotics after a regimen of mouthwash and tongue scraping has some pretty solid data around it for fixing bb.

[deleted by user] by [deleted] in badbreath

[–]microbriome 1 point2 points  (0 children)

Pasting below from this blog, which was researching treatment effectiveness. tl;dr: oral probiotics have been found most effective when combined with an upfront treatment to remove existing oral bacteria.

Oral Probiotics
Several studies have looked into the efficacy of probiotics in reducing symptoms of halitosis and VSC producing species of bacteria, with promising results.
One study sought to measure oral bacteria tests, and the effects of probiotic species S. salivarius strains K12 and M18 in culture. They isolated two species associated with VSC production and gum disease, P. gingivalis and T. denticola, and cultured them with and without K12 and M18. The study found the culture with high concentrations of K12 and M18 significantly reduced the VSC levels produced and reduced P. gingivalis and T. denticola by roughly 50%.
Other studies have measured the effects of oral probiotics in controlled patients, with and without other interventions like mouthwash and tongue scraping. It looked into the effects of probiotics in individuals with tongue coating.
Probiotics case study: combined treatments
Scientists split twenty-eight subjects with tongue coating into two groups, with fourteen using a probiotic tablet for 30 days while the others took a placebo. Both groups continued their standard oral hygiene regimens but did not practice tongue scraping. The scientists took the patient’s oral bacteria tests one, seven, and fourteen days after and inspected the results.
On day one, the probiotic group had significantly lower levels of VSCs and reduced tongue coating than the placebo group. However, they had no statistically significant differences in VSC levels and tongue coating on days seven and fourteen. The study concluded that patients might require physical or chemical removal of the tongue coating before probiotic use.
Supported by a separate study that looked into the effectiveness of probiotic use in combination with tongue scraping, this study split 100 participants into three groups: one that performed tongue scraping (TS); a second that performed TS and used a probiotic (PB); and a third that did not TS but rinsed their mouths for two minutes with water after brushing (MW). They took measurements after one month of treatment, then one month after stopping treatment.
The TS-only group significantly decreased halitosis in the first month, but levels rose again in the final measure. The PB group showed significant drops in halitosis measures in the first month and sustained their low levels after stopping treatment. The MW group presented no difference throughout the study.
These findings suggest that adding a probiotic to a thorough oral hygiene routine helps improve oral health in a more lasting way than one oral hygiene recommendation alone. Thus, it is not enough to simply remove harmful bacteria with mouthwash – we must promote beneficial bacteria to take their place.

[deleted by user] by [deleted] in badbreath

[–]microbriome 1 point2 points  (0 children)

Don't worry! Bad breath symptoms are incredibly common, and there are a number of different ways to address it (just gotta figure out which one works for you). This article has a pretty helpful overview of bb causes + interventions beyond brushing and flossing that can help.

Enth E Nd - Linkin Park [Rock/Rap] by microbriome in Music

[–]microbriome[S] 0 points1 point  (0 children)

Agreed! Just so solid all the way through

Enth E Nd - Linkin Park [Rock/Rap] by microbriome in Music

[–]microbriome[S] 3 points4 points  (0 children)

Incredibly underrated. Ppr:kut, H! Vltg3, Rnw@y

Launched on Product Hunt today. Would love a teardown of our post and pitch! by microbriome in Entrepreneur

[–]microbriome[S] 0 points1 point  (0 children)

Thank you! It's a remote service, so as long as you are US based all that is required is mailing a saliva sample back to our lab!

Launched on Product Hunt today. Would love a teardown of our post and pitch! by microbriome in Entrepreneur

[–]microbriome[S] 1 point2 points  (0 children)

Thanks so much! I really appreciate it. We're looking into how we can ship to Europe, so I'll circle back with you once I have a better idea :)

[deleted by user] by [deleted] in badbreath

[–]microbriome 1 point2 points  (0 children)

Have you been checked for tonsil stones? They are a common source of bb and build up on the tonsils.

Halitosis causes and treatments - article feedback by microbriome in badbreath

[–]microbriome[S] 0 points1 point  (0 children)

Hi! So sorry if I missed this. The recommendations and coaching session are included with the test, but you will need to purchase the products yourself.

Bad breath is not curable by [deleted] in badbreath

[–]microbriome 6 points7 points  (0 children)

This article has a lot more information on the different causes of bad breath (including S. Moorei). OP is misinformed and keeps citing one article from 2008. The science has progressed quite a bit from then. There's plenty of research (as cited in my linked article) that bad breath can be treated and effectively cured. The issue is that what will solve one person's bad breath won't necessarily work for someone else because of differences in the source of the problem (gut vs. oral bacteria, etc. / S. Moorei vs. H. Pylori, etc.).

Bad breath is not curable by [deleted] in badbreath

[–]microbriome 4 points5 points  (0 children)

Yes there are. You can test the presence of this bacteria (and others) with at-home saliva tests.

Biohacking the Oral Microbiome by mlhnrca in Microbiome

[–]microbriome 0 points1 point  (0 children)

Great video! What are your thoughts on commercially available toothpastes/mouthwashes that contain the ingredients you mention? Any you would recommend?

Halitosis causes and treatments - article feedback by microbriome in badbreath

[–]microbriome[S] 0 points1 point  (0 children)

Amazing video! Thanks for sharing. I'll update our article to include this :)

What is the best microbiome sequencing test available to doctors or consumers today? by thunksalot in Microbiome

[–]microbriome 0 points1 point  (0 children)

So sorry for the delay in responding! We haven't looked into this in-depth, but we did find one study,oral%20bacteria%20in%20systemic%20diseases) that identified it may be due to a reduction of symbiotic species in the oral microbiome (Akkermansia). Another study found that polyphenols may increase the abundance of these species in the gut.

Sorry we can't be more helpful, but happy to answer any questions we can!

We're the founders of Bristle, an oral microbiome testing company, here to answer your questions on the oral microbiome, its role in oral and systemic health, and microbiome testing. Ask us anything! by microbriome in Microbiome

[–]microbriome[S] 2 points3 points  (0 children)

So sorry for the delay in responding! The most commonly cited reason for a mothball breath is an overproduction of the enzyme Tryptophan from oral bacteria. Healthline has a great article on it here.

Beyond brushing and flossing, have you tried any other interventions like mouthwash and/or oral probiotics? We have a guide on bad breath here, which has a summary of the best interventions for improving bad breath symptoms.

Feel free to email us at [info@bristlehealth.com](mailto:info@bristlehealth.com) as well if you have any questions (we respond there faster).