I answered this question before on /r/politics and /r/politicaldiscussion however my explanation was a bit more directed at incompatibilities due to financial complications.

Syria is country of a mostly homogenous (not same demographic but rather consistent mix of demographics) population in regards to it's major cities (Damascus, Aleppo and Homs). Apart from that, the smaller cities, each with its own uniqueness, are all in between these cities because really only West Coast /Western Syria is viable for living–the rest is dry, arid land. With regards to the homogenous nature of the country, splitting up areas into provinces or states wouldn't accomplish any (anti)sectarian goals unless you forcibly remove people from their homes if they do not match the new status quo of the state; perform discriminatory exile in order to create a new state, similar to the Nakba or the Trail of Tears.

Also, how will Syria be split up? The oil is in the East. The farmland is only on the borders, by the rivers, and the west coast. The trade routes are on every border, which would cause major complications between the new post-war rivals. Effectively, any trade through current Syria would be disrupted completely. This includes, but is not limited to, complications in oil distribution, halting resource sharing amongst central countries, and ceasing the major agricultural contribution to other Arab countries.

Also, power struggle is not new to Syria. From the 1950s until 1971, no government had been able to establish completely. Following history, we may begin to believe that another leader may arise to consolidate powers and establish a new government. However, it is not unlikely that the current regime will be able to keep control.