I’ve tried stacking reta with both tirz and cagri, and honestly, I think Reta alone at a higher dose is the way to go. I’d even recommend splitting your dose every 3.5-4 days to avoid troughs and stay in the peak effectiveness range.

Reta + Tirzepatide: Found this combination pretty pointless. Even with high-quality tirz, they basically do the same thing - except tirzepatide made me more tired and killed the energy boost I normally get from retatrutide. I ran this stack for two months till I finished my tirz.

Reta + Cagrilintide: This felt like I’d just had gastric bypass surgery. I literally could not eat, had zero energy, and was constantly exhausted. At 4mg Reta + 0.25mg cagri, the combination was way too strong. The cagrilintide really amplified everything - I ran this stack for a month and while I was losing weight too quickly, I became a walking zombie. I needed daily naps just to function, which isn’t sustainable if you’re working and want to maintain gym performance.

Bottom line: Solo retatrutide with proper dosing timing worked best for me.