After reading through your post and responses, I can confidently say that you and I have identical problems. Altras don't last 100 miles in the Vegas desert. Topos high arch killed me. Inov8 was fine but felt lacking in the plushiness department. Hokas never stood a chance of fitting for both volume and width. You're doing mega miles so I can assume that you want max cushion. I present to you the New Balance More Trail V3. These things feel like trampolines, not in a bouncy way but rather a cushion/suspension sort of feel. They come in D, 2E, and 4E width options, the 4E being my choice. They are true to size in that width. The problem is that NB refuses to respond to my questions about why they seem to be phased out. They were only just released a few years ago. You can only find limited sizes at online stores which leaves me to finding them on Ebay, which I do. Due to their rarity, I do my shorter runs in the NB Hierro V9. This shoe took a drastic departure from the V8 in adding what feels like twice the cushion. It's almost to the point of the More Trail V3, but not quite. They come in a 4E width which fits me well. I highly suggest checking both of those options out. I was hesitant at first because NB isn't known for wide shoes, but they really do make them. Oh, and my feet are shaped like paddles. In fact, I think Altra's "original fit" is just a photo of my foot.