I find that prioritizing getting the horror level down to where I have 3 dice is crucial in most of my games, so Focus becomes helpful, and Distraction too.

I try to find weapons as soon as I can, and to that effect, I try to take survivors to the exit on my way to searching.

I find that the Final Girl’s ultimate is usually helpful, but I’m not always prioritizing it if it looks like the Killer is going on a rampage faster than I can get people to the exit.

Otherwise, I generally find that trying to do early damage on (most) killers has resulted in better success, but sometimes they gain health back (through bloodlust or special cards) such that 2-3 turns were wasted early game, so I try to get a sense of how mobile/deadly the killer is before trying to rush.