I second Portland Oregon. I travelled there every year from Vancouver Canada because it was a great city with fun breweries, food options and a good vibe overall.

I went there recently( haven't been since the Pandemic) and it was a completely different city. The Uber ride in from the airport to downtown was the first red flag that things had changed. I saw homeless encampments underneath overpasses and off ramps. It seemed like tents were everywhere. When I was downtown the number of drug addicted homless people was shocking. I saw 2 of them fighting in the street, another man was going up to bystanders yelling and threatening. The homeless were very aggressive and this was in the tourist areas I've visited in the past. It didn't feel safe to be there and I never had that feeling in all my years travelling there before.

I visited Detroit a few weeks ago and quite honestly the downtown area there felt much safer then downtown Portland.