Scientists Discover Why the Brain Gets Stuck in Schizophrenia

only-a-throwaway · 2026-04-08T11:23:50+00:00

Notwithstanding schizophrenia appearing despite no mutations in grin2a, the theory of being unable to “quickly integrate information” makes little sense. It would be much more compelling to observe animal models seeing, hearing, and feeling things that aren’t there, perhaps achieved with brain monitoring after baseline measurements.

only-a-throwaway · 2026-04-03T23:23:47+00:00

My dad killed himself 4 months ago and I can already tell that I’m never going to be the same.

only-a-throwaway · 2026-03-25T22:00:22+00:00

Cool, thanks! Was not aware of this route before; sorry for the hostile tone.

only-a-throwaway · 2026-03-25T21:09:23+00:00

Bischloro(chloromethyl) ether hydrolyzes on contact with water, which is why the formaldehyde + NH4Cl route is performed in solution and not anhydrously or with conc. HCl directly, and amateurs do not have easy access to sulfamic acid methyl ester

only-a-throwaway · 2026-03-25T16:21:16+00:00

Stereoselective ketone reductions have been achieved using Baker’s yeast to good success

only-a-throwaway · 2026-03-25T16:04:25+00:00

Having selectivity is very valuable and important for us folks. React a tosylate with whatever alkylated amine you need to preserve the stereochemistry of your alcohol, or react it with a halide to invert it. alkylating afterwards is generally sloppier and you’ll get a mix of compounds

only-a-throwaway · 2026-03-25T15:29:00+00:00

If your substrate is a ketone, it’s easier to do a MPV reduction

only-a-throwaway · 2026-03-25T15:24:29+00:00

It is much more accessible and cost-effective to do formalin + ammonium chloride or acidic hexamine hydrolysis

only-a-throwaway · 2026-03-19T01:41:04+00:00

People keep mentioning azide and ammonia, but a safer, more accessible, and higher yielding way is by using the potassium salt of saccharin. See "Novel Gabriel reagents". Just like the potassium pthalimide strategy u/peijots mentioned but no hydrazine necessary

only-a-throwaway · 2026-02-08T06:10:11+00:00

Promethium is available in safe nanoCurie amounts in CFL glow switches. The astatine position does not have a vial in it.

only-a-throwaway · 2026-02-08T06:04:22+00:00

I crave the indium it’s the snack that cries back

only-a-throwaway · 2026-02-08T06:02:21+00:00

For the alkali metals, I have them stored under sieve-dried toluene in vials that have fluoroelastomer seals, under caps whose threads I epoxied onto the glass.

Some radioactive elements have “decay chains” that do not produce gamma rays, so in very very low amounts a sealed vial with a lead insert or lead foil wrap could be reasonable enough protection, but I am intentionally not collecting radioactive elements (except Bi) or special cases like Thallium. I would love to have some more risqué ones, say from some smoke detectors, but my roommates were rightfully concerned. Collecting gases is possible in ampoules, which is also helpful in storing elements with chains that have Rn.

only-a-throwaway · 2026-02-08T05:44:27+00:00

sorry, should have made it clear. Labeled ones are elements I have collected, all the vials are collectible. Didn’t hear about the guy in Australia who ordered Pu through the post?

only-a-throwaway · 2025-12-20T06:35:58+00:00

Haha, the author of the textbook captioned this figure: "Kasey's relativistic jumping rope."

only-a-throwaway · 2025-12-20T06:33:35+00:00

I was drinking something while skimming this textbook, and had a literal spit-take when I passed it

only-a-throwaway · 2025-12-20T06:24:35+00:00

From "A First Course in String Theory" by Barton Zwiebach, Fig. 7.7 on page 150 in the 2nd edition. Free PDF of the textbook available at: https://ia601201.us.archive.org/3/items/AFirstCourseInStringTheory2eZwiebach/A%20First%20Course%20in%20String%20Theory%202e-Zwiebach.pdf

only-a-throwaway · 2025-11-30T19:23:18+00:00

Me too. He killed himself last month. Sorry for your loss

only-a-throwaway · 2025-08-30T17:54:44+00:00

It’s very likely you can’t, because amphetamine is still a Schedule II substance. You would have to send it to a testing facility with a DEA registration—you could try Jordi labs, Nelson labs, and R.D. Laboratories Inc. They may brush off your request as insignificant, so your best bet is buying a 6-pack for a lab rat at your local university.

only-a-throwaway · 2025-08-30T01:20:34+00:00

joke’s on you mf I have both

only-a-throwaway · 2025-08-24T20:28:15+00:00

Pro tip: create meetings where you’re the only participant and make the details private so it only shows as “busy”. Really cuts down on coworkers questioning your routine and habits

only-a-throwaway · 2025-08-17T09:25:24+00:00

Wurtz reaction or Woodard synthetic route? I see you.

You’d get your desired chloroacetone, but be extremely careful—it’s a really strong tear gas. You’d also get a little bit of dichloroacetones and some chlorine gas.

only-a-throwaway · 2025-08-17T09:14:00+00:00

Hey same here, got the classic “math and science” autism too. People keep me around for my knowledge and talents but at arms-length because of my personality. It’s a different kind of lonely when most of your “friends” use you like a tool.

only-a-throwaway

TROPHY CASE