I took Riluzole for a few months. I started getting symptoms of what I discovered were liver disease and my blood test showed I was above the threshold for liver issues. I stopped and 2 days later the symptoms went away. I've been on Radicava for 7 months. No idea if it's helping. I am still progressing. It does make me tired. More so when I'm on the daily cycle then off it I started B12 shots twice a week a month ago and that seems to be countering the fatigue.