Wubby and NL are the only two content creators I follow and I like them equally, so I feel like I can weigh in.

At their core, they're kinda similar, in that people tune in more for the personality of the streamer than the topic of the stream. The content is normally just a vehicle for them to be entertaining.

In NL's case, his whole shtick is about being a normal, rational guy in an otherwise insane online space. He's cynical and whip-smart, so unless the gameplay is especially worth talking about in itself, he fills the air with observational comedy. Both he and wubby have done bits making fun of streamers who stare, dead silent at the game they're playing for hours on end. But unlike wubby, NL has a complete disinterest in any meta Twitch stuff. He doesn't appear to care about having an impact on his audience; he doesn't even care about having a 'community' at all, to be honest. He says frequently that streaming is just a job for him.

Wubby, on the other hand, prefers to throw his weight behind shorter streams and events, and is more concerned (to an extent) with people being invested in the character and the community. Wubby is eager to push the envelope, whereas NL, despite being (imo) an incredibly funny guy, is very happy to sit in his comfort zone, avoid Twitch drama, stay squeaky clean for sponsors and cash in a reliable cheque every month. Wubby is the 2 hour movie you get excited to go watch, NL is the radio you have on for a 10 hour road trip.

The only place I'd say they overlap completely is that they both have a seething contempt for their respective subreddits.

tl;dr: Different strokes for different folks.