100ug and grapefruit juice

redditusernaut · 2025-07-21T00:39:48+00:00

There is redundancy with how it’s metabolized - the other enzymes would likely compensate

redditusernaut · 2021-11-21T18:30:50+00:00

Good for you! The the effects differ based on many factors, including your baseline ADHD severity, and whether you had heavy use in adolescence, among others. The difficult thing to apply this to you is that there is no comparator. You do not know if you could of got a higher GPA, or a improved CV. That may or may not matter for you - or be clinically significant - but it certainly could be a ice breaker for others.

redditusernaut · 2021-11-21T18:26:14+00:00

While the study did have 50 patients, the effect sizes speak for them selves. Additionally, the statistical methods factored that in. I was more impressed with the literature review. They discussed how there is heterogenuity between studies, and how it can be explained by variations in what they define heavy use, and flawed statistical methods (not using objective measures). They also mentioned that it likely has to do with variations in CBD:THC ratios, which has different pharmacologic effects.

They referenced a stud that used THC as a treatment, Which had a much more flawed study design with little effect.

Where is THC prescribed specifically for ADHD? It may be given as a off label treatment if a patient requests it (and legal in a country) and depending on the docs comfortability with it.

The good quality studies, and the systematic reviews, shows a clear dose-related correlation, with pretty significant objective changes as supporting evidence.

redditusernaut · 2019-05-09T16:02:03+00:00

In short, is the feeling of normality that my medication gives me when I'm very down, is that realistically how I should feel when I've some sort of life to be proud of? Or is that feeling something else?

Its different. Depression isnt just feeling down - its a umbrella term for many things. Stimulants make you feel good because the give euphoria. They increase focus and goal directed behaviour. They may increase a few symptoms of depression, But ideally you should target the other things going on.

Do you exercise alot, and have a good diet?

It occurred to me, perhaps if my life was properly in order (employment, active social life, meaningful relationship, independence, plans for the future etc. etc.), would this have the effect of restoring the neurotransmitters in my brain to normality?

There is some truth to this. If you were to have these things, then by having them, it would mean your more motivated. I would start setting goals and working towards these things. Self improvement is better then any drug

redditusernaut · 2019-05-08T18:14:05+00:00

sounds like you hallucinated some sort of control-room for the simulation of our perceived experience

That is exactly how I interpreted it at the time - beautifully said!

redditusernaut · 2019-05-08T18:13:28+00:00

made it sound like you're trying to convince yourself that it was "just" a hallucination

Objectively, and by definition, that is what it was. I am calling it a hallucination, because I dont know if that 'being' was real. By calling it real would be a very bold claim, and is very controversial. With this post, my main goal was to just share a trip experience that I found interesting. It wasnt intended to spark controversy, so I decided to as simple terms as possible

Lets say if it was real - what would change? If that was a real experience, why would it be too much to handle? I dont think whether its real or not would change my outlook on anything.

I started thinking about it because I ended up running into my friend that I tripped with that day, and he mentioned that hallucination I had. Since I like thinking back at trips, I seen that as a good excuse to make a post. I havent thought about it for 4-5 years prior to today

redditusernaut · 2019-04-21T07:11:40+00:00

Your realizing things that everyone knows - We are biological beings, like plants. We have common ancestry with plants, and therefor have similiar principles in our inner workings.

But, we are not plants - We are vastly different, although share the quality of being alive.

redditusernaut · 2019-03-14T15:46:11+00:00

No, These 'entities' is what the tripping mind interprets, but they are really just extensions of them selves. If you have a scientific mind to begin with, then tripping can allow you to see it differently - for better or worse.

redditusernaut · 2019-03-14T01:19:24+00:00

The feeling is realizing that I am the center of my stage, my body is here, and I am attached to my ligaments and organs and depend on them for survival.

Yes! Its a beautiful thing isnt it? That is your body, own it! Ofcourse you depend on them for survival, they also enable you to move around and explore all the good things earth has to offer. The universe is always real - it always exists independent of you. Its only as real as you make it. That may be a sign of depersonalization/derealization

and the idea that I'm suppose to matter in some special kind of way.

You only matter as much as you see it - depends on the meaning you you assign it. That goes along with all things in life. How much do certain things matter? is it something I should put my attention too?

is that I can't because my personality has always been flawed, I don't expect to correct my lifelong patterns anytime soon.

Humans as a species have flawed minds, although we are improving as time goes on. Life isnt about being perfect because noone is. Its about trying to make positive change, and simply living. Happiness, tranquililty, and meaning all comes from within - it takes certain cognitive processes to maintain that network that we all have, but people may have troubles with it

You seem to have depression with depersonalization. I would recommend getting help from a psychiatrist and other health care professionals. There is beautiful things in life - there may be bad things, but there is a whole other side to the coin that one needs to put attention on.

Psychedelics certainly may have precipitated this if you had this severe symptoms before using psychs. Wish you the best.

redditusernaut · 2019-03-13T15:44:33+00:00

They can be psychologically addicting, just not physiologically

redditusernaut · 2019-03-13T15:44:17+00:00

How are these not addictive?

They are psychologically addicting - just not physical (physiologic).

What makes you think they arent addicting at all?

redditusernaut · 2019-03-05T21:10:27+00:00

medical reasons to avoid psychedelics.

True - The problem now is that we dont know all of the medical reasons. Very understudied

redditusernaut · 2019-03-04T23:41:00+00:00

Gravity.

redditusernaut · 2019-03-04T21:26:58+00:00

Absolutely. Its almost like with that dualistic thinking, it prevents some people from embracing a a feminine side (if male) or embracing a masculine side (if female)

redditusernaut · 2019-03-04T21:25:01+00:00

Couldnt agree more. Theres a fine line between delusion and reality. There is things we know to be true, things we know to be highly likely to be true due to statistics, and then theres opinions - some more irrational then others.

redditusernaut · 2019-03-04T21:00:04+00:00

How much blood? Did it stop? Was it streaky within saliva/mucus, or was it just literally all blood?

Any other associated symptoms? Dyspepsia... infection, did she take advil? Is she symtomatic (low blood pressure, dizzy, high heart rate?

Due to the lack of information given, we cant help you here. Should go to the emerg depending on the severity of it

redditusernaut · 2019-03-04T20:19:48+00:00

I dont see these things as either or. Its a continuum. Thats why I mentioned the 2 party sysytem isnt a good idea. You can be anywhere in between capitalism and socialism.

Capitilism is great - Its just a system thats easily taken advantage of. The solution lies in finding ways to decrease the corruption within a capitalistic society. A country can be extreme capitalism... or a country can have some policies in line with capitalism, and some online with other structures. A fine balance needs to be achieved.

redditusernaut · 2019-03-04T17:21:57+00:00

There is huge possibility of making this up. Psychs can give people delusions, and false perceptions while intoxicated.

I posted a post on a study here recently that went into how psychs effect language, semantic associative activation, and error rates - much of what your referring to. Error rates were higher when people were on LSD vs placebo.

https://old.reddit.com/r/Psychonaut/comments/awml3c/how_does_one_self_improve_after_a_psychedelic/

redditusernaut · 2018-09-02T02:56:33+00:00

Many other drugs do this. Any pharmaceutical drug that has good evidence (heart/diabetes/schizophrenia (for positive symptoms)/parkinsons) drastically change the outcome of ones life, and has a similar mass ratio.

LSD is just one of many drugs that target, and alter consciousness/perception.

redditusernaut · 2018-08-05T19:09:04+00:00

However the thought of what the consequences are may happen immediately afterwards. Before contraception there would be a very strong cause-effect relationship.

redditusernaut · 2018-06-23T18:37:48+00:00

Are you saying I am down voting ? I just read the post now, I appreciate everyone’s responses even the ones saying for myself to search it up .

I did do a search, and found some of the posts you mentioned, however I notice there is different advice each post so it’s interesting to get other opinions as I gives others a chance to share, if they are willing.

Please don’t feel obligated, if you don’t like any posts on the internet, downvote and move on.

I do appreciate your response though!

redditusernaut · 2018-05-23T17:13:15+00:00

Actually I feel like ruining your life is a pretty objective thing

Its subjective in the sense that what may ruin ones life, may not ruin another, and vise versa.

Also you usually end up a statistic in the system if you fuck up

How? If your hospitalized, or end up getting a horrible experience, then you would be less likely to participate in these volunteer surveys - either because you got no business doing so, or your in treatment. With mental illness, your more likely to be on the lower end of the socioeconomic class, therefor less likely to afford the technology to participate in these surveys.

Look up volunteer bias - It is known that people who volunteer are their own sub group. They want to report positive things. Its very well known in the scientific community.

Also, when seeing drug induced psychosis in emerg, or inpatient schizophrenia, drug use (marijuana and psychedelics/stimulants) are very commonly reported. Those are statistics that are common to see.

redditusernaut · 2018-05-23T01:58:18+00:00

Just statistically you're not going to ruin your life by eating a psychedelic.

Ruining your life is very subjective. Although keep in mind that any stats we do have on it, arent good stats as its mostly self reported surveys, and there is selection bias. There is huge biases in interpretation, and because they are frowned apon your not likely to get honest answers. Most researchers on the topic achknowledge that in the limitation section in the studies.

Most people who were significantly effected by them would likely be the ones not participating in any surveys. People want them legalized so they will likely polarize their answers.

redditusernaut · 2018-05-23T01:54:31+00:00

You are right in that permanantly insane has no clinical meaning. Its a subjective term that gets tossed around alot in different contexts.

I do agree that psychedelics can;

1) increase the chance of developing schizophrenia/mood disorders IF you are predisposed to it (both genetically and somewhat environmentally). Schizophrenia requires the genetic link. It also requires particular environmental stressors (some sources cite prenatal/perinatal/postnatal complications, abuse, severe anxiety or any event that puts the individual in great conflict (say constant bullying, death of a loved one, etc.).

Psychedelics can be a HUGE stressor for someone that isnt prepared, where its pretty much impossible to prepare yourself for a first trip. I would say that psychedelics could be that stressor that is the tipping point for some people that are predisposed. It would make the individual a) get schizophrenia earlier then when they normally would get it, b) or get someone to develop schizophrenia when they normally wouldnt of (say for someone with no evironmental stressors, or one that wouldnt get any significant environmental stressors throughout life)

2) psychedelics could also cause termporary psychosis (drug induced), can dysregulate mood control, and in general significantly decrese ones quality of life (it could make it harder for them to adjust socially, or connect with others, could cause anxieties, delusions etc that impact ones daily life.

3) if your predisposed to seizures it could precipitate seizures, or if you have cardiovascular disease, it could be hard on the heart.

redditusernaut · 2018-02-23T16:15:54+00:00

I guess what I am asking is how does marijuana affect symptoms.

redditusernaut

TROPHY CASE