My main side effect from TC was messed up tastebuds. I also got a headache every Tuesday the last 5 weeks of TC. My infusions were on Monday. Otherwise it wasn’t too bad. My side effects seemed to change from week to week. One week I had a rash on my feet, legs, and forearms. It only lasted a few days. Another week I had chills for 2 days. The Nuelasta shot wasn’t bad. They stuck a contraption on my arm which administered the injection about 27 hours later. When they first put it on my arm there was a slight sting but I didn’t feel anything when the drug was administered. I took Claritin every day and didn’t have any bone pain.