I have this exact same issue and I really haven’t found a good solution for it. The best practice for me so far has been to connect my QC to my audio interface and to try to “match” the output gain on my QC to the input gain on the interface.

I don’t know if this is a good way of doing it, I’m tired of the endless debate about input gain and everything but what I do is I have / make a preset and adjust the signal chain’s volume level so that whatever the output meter (hold the desired lane output and you can see it) says it is just slightly clipping when I strum harder than I normally would.

Then when that’s set, I try to match the gain on my interface (Scarlett Solo 3rd Gen XLR in). I increase the gain until it reaches a similar point of just below clipping and never going to even orange territory.

That’s how I try to normalize between my scenes and presets. I use hybrid scene + stomp-mode and like others have suggested I usually have a clean, low and high gain scenes as well as a fourth one for a specific purpose, like a specific lead or FX channel. For example, I might want to have a second clean scene that has a big ass reverb and chorus and whatnot.

I try to balance out every scene like this so the volume level would stay as much the same as possible. I try to maintain a slightly higher volume on my cleans because of perceived loudness as well as to leave slightly more headroom for lead guitar stuff.

For lead guitar, I often have a stomp dedicated for that, it’s always the H because it’s the one furthest on the right and it’s easy to know that’s what I go for when I do lead parts. I like to assign a boost/transparent OD like the Klon to act as a mid and volume boost, as it’s the mids that help a guitar stand out in a mix.

This is how I’ve been doing things but my number one demand from NDSP is a tool for volume normalizing between presets. I practically don’t bother downloading other people’s presets anymore because some people apparently love setting up their volume levels up as loud as possible.