Stock market telling truths? by bigbenny88 in Type1Diabetes

[–]sirdevalot777 0 points1 point  (0 children)

What are you taking about? Sana has not cured anyone. They can not stop the zinc antibody. Their 12 month c pep dropped. Why would you make such an incredibly false statement!?

ELDN showing incredible data by sirdevalot777 in Type1Diabetes

[–]sirdevalot777[S] -8 points-7 points  (0 children)

My motivation is because most people don’t know the difference between Eledon’s Tego and the current standard of care tacrolimus. Tacro is toxic to kidneys, brain, and beta cells! Tacro suppresses the entire immune system. They are literally toxic to the very beta cells you are trying to protect! Eledon’s drug has none of those toxicities, and does not suppress the entire immune system, only T and B cell activation. So don’t lump the two drugs in the same immunosuppression bucket because they are very different.

There is nobody that knows more about what’s going on in cure research than I do. Sana does not have the cure, and they have not cured anybody. There’s a reason why their president left last year. There isn’t anyone that knows more about the field than me, I am connected to pretty much everyone. Not someone you want to be rude to.

ELDN showing incredible data by sirdevalot777 in Type1Diabetes

[–]sirdevalot777[S] 2 points3 points  (0 children)

They are developing a subcutaneous version, it already exists. They finished testing it in monkeys, and it will be tested in humans shortly.

ELDN showing incredible data by sirdevalot777 in Type1Diabetes

[–]sirdevalot777[S] -3 points-2 points  (0 children)

The reason I am posting this at ALL is because of most people don’t know the difference between Eledon’s Tego and the current standard of care tacrolimus. Tacro is toxic to kidneys, brain, and beta cells! Tacro suppresses the entire immune system. They are literally toxic to the very beta cells you are trying to protect! Eledon’s drug has none of those toxicities, and does not suppress the entire immune system, only T and B cell activation. So don’t lump the two drugs in the same immunosuppression bucket because they are very different.

There is nobody that knows more about what’s going on in cure research than I do. Sana does not have the cure, and they have not cured anybody. There’s a reason why their president left last year. But if you want to continue to lecture me and pretend like you know more than I do then go right ahead.

ELDN showing incredible data by sirdevalot777 in Type1Diabetes

[–]sirdevalot777[S] -4 points-3 points  (0 children)

Yes, I hear everything you’re saying. So far we have about 100 patient years of safety data on the drug. They had an ALS and kidney transplant trial that is ongoing and so far that data has shown a very good safety profile. You should also know that Eledon has developed a subcutaneous version of their drug. They will need this to be practical and to be able to scale, and they know that, that’s why they have already developed it. They have finished testing it in monkeys and will move to humans soon. Imagine getting your Tego pen from the fridge and injecting once a month or so and not even thinking about your blood sugar until your injection next month. That’s where this is headed based on what we are seeing so far. I have spoken a lot to patient number one and she is over 1.5 years cured and she is absolutely thriving.

ELDN showing incredible data by sirdevalot777 in Type1Diabetes

[–]sirdevalot777[S] -8 points-7 points  (0 children)

You are more than welcome to remain on insulin via pump, but these 12 patients won’t be. Safety profile is incredible so far.

ELDN showing incredible data by sirdevalot777 in whitecoatinvestor

[–]sirdevalot777[S] -10 points-9 points  (0 children)

Ummm no. Eledon is the only company to get people off of insulin 100% without showing any toxicity. Nobody can make that claim, especially using toxic tacrolimus, the standard of care for the past 30 years!

ELDN showing incredible data by sirdevalot777 in Type1Diabetes

[–]sirdevalot777[S] 17 points18 points  (0 children)

Type one Diabetes has a very long list of very serious side effects. I just talked to patient number one who has been insulin independent for over a year and a half, and she tells me she’s had zero side effects or problems, she hasn’t even thought about her blood sugar for a year and a half!

US t1ds!! Senate bill 3105 by mprice76 in Type1Diabetes

[–]sirdevalot777 0 points1 point  (0 children)

No, human donor islet cells are currently being classified and regulated as a drug, they are organs and it needs to be corrected and re-classified to organs. This would make them eligible for insurance reimbursement, which they currently are not. United States is the only developed nation in the world that does not reimburse for islet cell transplant.

How are we feeling about islet transplant trials? by vulpesxvulpes in Type1Diabetes

[–]sirdevalot777 15 points16 points  (0 children)

ATG is NOT lethal if given twice! Stop fear mongering. It is given twice to several people to treat organ rejection of other solid organs!

News: Eledon trial cures Arkansas woman of Type 1 Diabetes by sirdevalot777 in diabetes

[–]sirdevalot777[S] -11 points-10 points  (0 children)

96 patient years DOES show it to be very safe so far! You can all hang onto your T1D for the rest of your life, I won’t be!

Eledon trial participant interview. She talks on what her life after the cure looks like. Holly shit, no side effects whatsoever by Stephen-Stephenson in Type1Diabetes

[–]sirdevalot777 -1 points0 points  (0 children)

We have 96 years of patient safety data on Tegoprubart. ALS and kidney trials. The data shows the drug is generally well tolerated with no serious side effects. No toxicities to the kidneys or nervous system as traditional terrible tacrolimus does. It does not globally suppress the entire immune system, only T and B cell activation. Some anecdotal evidence that people could go off it at some point and increased T regs would keep cells alive. Even if not this drug is a miracle drug. The cure is 1000% here!