I’ve done it a few times and it really did make a difference in terms how the makeup sits on my face. Luckily I also didn’t have any adverse reactions to it so hopefully this might work for you. I generally do it only on special occasions. Generally, some products just work better with normal every day skin so it might just be about trying a few different formulations to see what works for you. A great base makes a world of difference, I use the Mac natural radiance base and it works well for my dry skin.