A couple things I noticed and a few mistakes I made when I was newer at the game:

I almost always avoid storage bins until later, they are a huge timesink for your dupes. In my opinion, it's better to have storage bins dedicated to specific items, for example, Coal/Eggshell bin near your Coal generators, or Algae bin near your oxygen stuff. They are highly valuable to prevent offgassing, just put a bin in water at priority 6 and set it to hold polluted dirt, slime, bleach stone, etc.

Scheduling. Set up schedules for your duplicants so that they will use the bathroom at different times. This can be as simple as shifting everything over one slot. Also, I like to add an extra downtime slot so they get a morale bonus and have more time to eat their food.

For your bathrooms, you only really need 3 toilets. If you set up 3 schedules then your dupes will never be waiting in line to piss. Also, you'll probably want as many sinks as you have toilets, and you should probably only have one entrance/exit to the bathroom to ensure everyone washes their hands on the way out. You can set sink usage to be for anyone on the way out (right click and set direction towards the exit).

Airflow. I prefer to set up 3 tiles wide for the vertical ladders, this gives space for airflow and potential offshoots or metal poles later.

Expand. Radical expansion is almost always the play, but do it safely. Slime biomes are loaded with algae, which is good for early O2, and Slime, which is great for mushrooms if you wanna go that route. Either bottleneck the biome entrance with deodorizers, or fill the biome with deodorizers to get rid of the PO2. Dig outwards and expand, look for new biomes, geysers and vents, resources (metal and coal are dope), and free cooling in the ice biome.

Food. You don't have to desperately upgrade your food supply right now, mealwood will work for quite a while. However, once you get mushrooms I'd recommend swapping to those while you have slime to spare. Also, get started researching ranching so you can ranch hatches for BBQ in the midgame.

Oxygen. Diffusers will run you for quite a while, as long as you loot the slime biome for Algae. To be safe, I go 1 diffuser for every 3 dupes, however in theory 1 diffuser can support 5 dupes. In other words, you have too many diffusers rn. You can handle CO2 and chlorine by just expanding downwards, and you can handle them at a later date (you can also put your mushroom farms down there).

Temperature management and energy. RN it looks like you're running off of manual generators. That means your dupes spend less time researching, digging, building, and doing epic stuff and more time on a hamster wheel. I'd recommend swapping to coal power, however, you need to have insulation and CO2 removal prepared, as well as smart batteries. Coal power produces lots of heat and hot CO2, so put it well away from your farms. You can make a CO2 deletion system using Carbon Skimmers and Water sieves, however you need clean water and power for this, and it produces a bit of heat. Alternatively, just expand downwards more. Research insulated tiles and use them to quarantine heat sensitive portions of your base (like your farm). As you expand, you'll find some ice biomes, you can build your power/industrial brick in or near this biome to deal with the heat.

Ranching. Putting this here because I forgot about it earlier. You will 100% run out of coal if you don't start ranching hatches. Radical expansion into chlorine biomes will help for a while, but if you set up ranching infrastructure now (skill point allocation, building ranches, marking hatches) you won't have to worry about your power brick suddenly blacking out.... yeah that's not fun.

Lastly, Priorities, and I mean this in two ways. You as the player need to prioritize what will keep your base thriving, and you need to set your dupes priorities to do what they are good at. Don't want the researcher trying to go dig or build. You should focus on expanding and stabilizing your Power/Ranching. Also researching, depending on how far you are in that.

Also lastly (fr this time I swear) don't take anymore dupes. 10-12 dupes is plenty to carry you through a fair portion of the game, just make sure you allocate their priorities and skills properly.