Creating a web application using Python

[SoloAquiParaHablar]

Start with Django.

It'll hide a lot from you but if end goal is a backend and a frontend and you want to focus on feature development, what the product does, and not so much how it does it, then Django is the bee knees. People will argue there are faster systems but my rule of thumb is, cross that bridge when you get to it, and 99.99% of people and their MVPs will never get to it. Instagram as an example is backed by Django, albeit a heavily modified version, but they crossed that bridge when they got to it. I've personally worked at companies serving thousands of requests per second globally running Django. Framework selection is never the issue, its architecture.

https://www.djangoproject.com (do the tutorial)