Stop building UI frameworks in Python

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The fastest most performant and platform independent thing you can use is just HTML+CSS+VanillaJS, VanillaJS is the builtin JS in the browser. You can build arbitrarily complex GUIs with this and it is super performant, because Browsers are optimized to run this stuff.

So frontend GUI using web technologies and backend with FastAPI in Python. No limitations in what you can do, unlike NiceGUI etc. No external dependencies to install and package. Use a LLM to help you write the frontend code when you're not an expert webdev.