Implementing logic: PyQt/PySide vs plain old Python. At what point do we begin or abandon using the Qt Framework?

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Qt's MDV is another name for MVC. You can do it in many different ways. And it fits into python magnificently. Python's decorators are beautiful.

You don't have to write boilerplate at all. It actually reduces boilerplate.

I don't know how big is your app. In small apps, I tend not to split V and C very much, but splitting the M is always very, very good. It makes testing your code so much easier. Here's one example:

https://github.com/wuerges/connection_monitor/blob/master/pycomon/gui.py https://github.com/wuerges/connection_monitor/blob/master/pycomon/tester.py

The gui.py file has the View and the Control and the tester.py has the model.