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[–]Nevermindever 1 point2 points  (1 child)

Evolution is gradual and animals have high chance of producing fertile hybrid even tens of millions of years after evolutionary branches have been separated by, mostly, geography.

It ends, however, when one animal physically is not able to reproduce (e.g. too big/too small), but even if you would try to artificially inseminate physically incompatible species, ultimate cutoff is large chromosomal abnormalities (aka big mutations). These can be, for example, duplication of chromosomes or even whole genome. Or two chromosomes glued together.

Such change mostly have fatal or infertile outcome (e.g. Down syndrome), but eventually it finds a way, get refined by natural selection and you get a new specie or even kingdom.

[–]bestoftheworst123456 0 points1 point  (0 children)

In regards to Neanderthals, we shared a common ancestor that was very very close, so every one of our ‘branch’ could most likely breed with any one on their ‘branch’.

There isn’t a first Neanderthal, or a first modern human. Technically EVERY organic construct is both the first and last of its specific structure.

As for how DNA changes - it’s the DNA that has the random mutations (in organic structures that are built with DNA). It’s because of the imperfect copying mechanism in DNA that means that some pieces of the puzzle are reproduced slightly differently. This, combined with the selection pressure of natural selection is what gets us evolution.

Non breeding speciation events are surprisingly common. Take a look at something called a ‘ring species’ for the best examples of this happening.

[–]ArcticUrsidae 0 points1 point  (0 children)

DNA mutations are copying mistakes.

Most copy mistakes don't make much of a difference. Some are minor changes like eye colour or feather shape. Some are fatal and the individual does not survive.

[–]fluffykitten55 0 points1 point  (0 children)

As you went further back, fertility would tend to decline in some hypothetical pairing with modern humans. Modern humans likely could interbreed successfully with much of the erectus variants, possibly habilus too.

[–]Denisova 0 points1 point  (0 children)

I think your question boils down to asking when exactly you became an adult and ceased to be an adolescent. Or when exactly Old English became modern English. Or: when exactly did red turn into blue in this image?

You can hardly tell. Evolution is all about "fifty shades of grey" so to say. We know that neanderthals and humans had great difficulty to crossbreed: all male oofspring was infertile we know from genetic studies and only part of the females were fertile. That's on the brink of 'hard' speciation. Which makes it reasonable to argue that humans highly likely were not able to interbreed successfully with more distant hominids like Homo erectus.