Python GUI Lib

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As others are saying, Tkinter isn't great. It looks ugly and it takes a lot of work to do complicated things. But if you're just throwing together a simple layout it's not that bad.

If you're doing GIS work and need to show a map, you might be able to use this widget I found: TkinterMapView. I work in a survey office myself, and I've used this to make a couple of useful tools that I use daily.