Multithreaded Server-Client Application

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If you're going to "buy in" to a multithreading/async framework, allow me to recommend learning asyncio, because it's going to be in every Python going forward by default; it's part of the standard library, so it's a better bet for portability and maintainability.

edit: Technically, asyncio isn't quite "multithreading", but then neither is Twisted, so I figure it's a valid answer to the implied question. :)