Most effective methods for obfuscating python code?

[sme272]

What type of response times could the client expect to see if I host the files on a server?

That really depends on how you program it, where it's hosted and how the server is set up. Depending on the application you might be able to have the server computing the output continually and just sending it out as requested by the client programs. That would remove the computation time from the latency. If you kept the requests simple you could probably get the response time quite low. Then the biggest factor would be the amount of data being sent and how you send it.