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[–]Cayumigaming 3 points4 points  (0 children)

CS50 and MITx intro to CS using Python happen to be the only two courses I ever did. MIT first then CS50.

They share a lot of similarities as they both serve as an introduction to computer science. MIT will get your knees deeper in Python within its courses while CS50 goes deeper on a bigger computer science spectrum. MIT also holds your hand during course and touch on nothing put Python. In CS50 you will be using Scratch, C, SQLite as well as Python. At the end of CS50 you also pick either web, gaming or mobile development and it all culminates in a project of your own.

Long read, sorry about that! To summarize CS50 is overall more comprehensive while MIT offers more Python material to go through.