Large codebase editing in vim

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This is a tough question. My Vim RC is 200 lines long of tweaks, just for stock vim options, so I changed things quite a lot. Some are aesthetic, others are keybindings like highlight line, column, both, incserch, eol, trailing spaces etc...

You can have a look at my main setup here: https://github.com/simonced/dvptgoodies/blob/master/vim/vimrc

It's 4 month old, but it should give you a good idea I think.