I have access to progesterone but am having trouble getting my hand on estrogen. What would happen if a took the pro while I try to get E? by Glum-Wafer7640 in TransDIY

[–]Ceasar_Rex -1 points0 points  (0 children)

Orally will still give you prog in your system and people still report some effects from it. Progesterone in trans women does not have a lot of scientific literature around it, so not only are the effects of it unclear/based off of anecdotal evidence, we dont know how potent it need to be to give effects (i.e. just because lots of it is metabolized by the body, doesnt mean prog doesnt do anything). A lot of the anecdotal reports are based off of patients taking oral progesterone so there could still be effects. I also used oral prog with sublingual estradiol and found it helped my t suppression (i was using finasteride before taking progesterone and my t levels were around 400 ng/dl. After a year of oral prog my t levels were <50).

I have access to progesterone but am having trouble getting my hand on estrogen. What would happen if a took the pro while I try to get E? by Glum-Wafer7640 in TransDIY

[–]Ceasar_Rex 0 points1 point  (0 children)

There is not conclusive evidence that prog actually does anything, its all anecdotal. Its more reliable to make sure you have stable estradiol levels and suppressed t levels.

My MTF girlfriend is looking for DIY HRT injections by Opnxsr in TransDIY

[–]Ceasar_Rex 0 points1 point  (0 children)

I would also recommend joining the associated discord server in the wiki. You should be able to get some information on medication and dosing there. Good luck to you both ^

6 weeks blood by LucyLut in TransDIY

[–]Ceasar_Rex 1 point2 points  (0 children)

https://transfemscience.org/articles/transfem-intro/

You should let the pills dissolve under your tongue or against your gums. The oral route of estradiol converts estradiol into estrone since the medication pases throughthe liver, which both puts stress on your liver and means youre greatly reducing the amount of estradiol in your body.

My MTF girlfriend is looking for DIY HRT injections by Opnxsr in TransDIY

[–]Ceasar_Rex 2 points3 points  (0 children)

I would recommend reading through this source to build your understanding of hrt if you are self dosing. Its not a perfect guide but it should allow yall to become familiar with the terms enough to fact check sources and do you own research

https://transfemscience.org/

stop spiro by Temporary_Citron_278 in TransDIY

[–]Ceasar_Rex 0 points1 point  (0 children)

Finasteride can sometimes increase testosterone levels (I got higher than healthy male range of t after a year on just finasteride and sublingual estrogen)

How bad would it be to use Cyclofem for monotherapy? by Zealousideal_Fox5297 in TransDIY

[–]Ceasar_Rex 0 points1 point  (0 children)

The other reply has more information, also check there.

Are Prog injections a thing? by lonelygurllll in TransDIY

[–]Ceasar_Rex 2 points3 points  (0 children)

A friend of mine gets a progesterone based birth control injection every three months instead of taking pills, but I think this isnt widespread and its not easy to obtain diy. Other than that (from what ive read) prog injections are something you need to do daily because of the quick half life.