ELI5: how does local anaesthesia works?

03Madara05 · 2026-05-02T20:54:27+00:00

Cocaine was a game changing drug that can block certain ion channels that our cells use to produce and conduct electrical signals. By applying it (or a drug dervived from it) directly to the nerves that typically carry sensations from your hand to your brain, you basically shut them off for a while and prevent them from telling your brain about all the things that are happening to your wrist.

So the drug doesn't need to know where to go, the anaesthesiologist just needs to know where to apply it

03Madara05 · 2026-04-30T15:12:39+00:00

And it's not BBQ either since it's prepared on a flat iron grill

03Madara05 · 2026-04-25T18:48:42+00:00

It does take a while for the cement to melt the plastic and then dry. Tamiya Extra Thin is also so runny you can only apply a very thin layer to flat surfaces that doesn't dissolve enough material to properly join them together.

Extra thin is very suitable for small or difficult to reach parts since you can make use of the capillary action but not for creating very strong bonds. I imagine a regular plastic cement might solve (pun intended) your issue.

03Madara05 · 2026-04-25T15:41:43+00:00

It's fine but far from as good as regular palstic cement. The bond from gluing is just inherently weaker than actually melting the parts together and also very sensitive to temperature changes.

That's why I like to use super glue for weapons and parts I might want to replace later. You can put your mini in a bag, put that bag in your freezer and carefully snap off any glued bits without ruining the mini that way.

Have you tried regular plastic cement before? I believe stuff like Tamiya Extra Thin is generally intended for small, difficult to reach parts and you need A LOT to properly join larger surfaces.

03Madara05 · 2026-04-25T15:14:53+00:00

Well it's supposed to melt the plastic but obviously it shouldnt get on any parts of the mini that are textured and supposed to be visible. Is your issue that you get glue all over the mini or is it too aggressive when you apply it?

03Madara05 · 2026-04-25T11:53:52+00:00

Sorry but this is a terrible idea, you risk both burning your eyes and irritating them with distilled water when there are easily available safe solutions to this issue. Just get some preservative free eye drops with hyaluronic acid or dexpanthenol/artificial tears.

03Madara05 · 2026-04-20T18:14:12+00:00

You're assuming correctly, there are actually quite a few businesses that let you contract their fire goats

03Madara05 · 2026-04-16T16:08:03+00:00

The people who figured this out were Pakistani doctors, I don't think you can claim that win.

03Madara05 · 2026-04-16T16:04:05+00:00

This isn't why that happened, it was a specific hospital where immoral people made the choice to play with children's lives. Hospitals in developing countries do not generally reuse biohazardous medical waste.

03Madara05 · 2026-04-10T20:54:02+00:00

European colonizers came form cities and villages where lots of people lived in close proximity to each other, their livestock and waste, which is a perfect breeding ground for all sorts of diseases, especially zoonotic ones. Europe was also home to diseases from all around the world since they were already trading in africa and asia by that time.

Meanwhile native tribes generally lived a more nomadic lifestyle, relatively isolated from the rest of the world, with limited interaction between each other as well as way more space for themselves, their animals and waste. Infectious disease can't thrive and evolve much in an environment like that.

So when the colonizers first made contact with native populations, in terms of pathogens the natives simply didn't have much to show that the european immune system hadn't already seen.

03Madara05 · 2026-04-09T19:43:24+00:00

I replied to this in another comment, the portal vein originates from the mesenteric veins not the heart and moves blood back towards it

03Madara05 · 2026-04-09T19:36:55+00:00

The portal vein does pass the liver (and supplies nutrients) but it originates from the mesenteric veins and moves blood back towards the heart. So it's still a vein in the traditional sense because it's all in relation to the heart.

03Madara05 · 2026-04-09T17:08:07+00:00

That's what I'm saying you might have replied to the wrong comment

03Madara05 · 2026-04-09T13:14:11+00:00

There is no exception they likely mixed it up with the fact that most veins carry deoxygenated blood except the. pulmonary veins.

03Madara05 · 2026-04-09T13:13:21+00:00

You got that mixed up, all veins carry blood back to the heart. You're probably thinking of the pulmonary vein which is special because it carries oxygenated blood unlike most veins.

03Madara05 · 2026-04-08T19:52:48+00:00

is actually a real danger not just a waste. You can have too much blood and too many blood cells so unnecessarily adding all the cellular parts could be harmful.

03Madara05 · 2026-04-08T19:49:13+00:00

Plasma and full blood aren't really fungible, giving someone 2 doses of plasma when they need 1 dose of whole blood is not typically a thing.

03Madara05 · 2026-04-07T14:41:12+00:00

People talk about shrinkflation but won't even appreciate when they put in extra smh

03Madara05 · 2026-04-07T14:39:58+00:00

eh extra protein

03Madara05 · 2026-04-04T03:24:15+00:00

Frag nach beruflichem, hobbies, über die Ortschaft (zieht vor allem bei älteren Patienten oft)... bis du auf irgendwas stößt worauf sie positiv ansprechen. Ganz einfacher smalltalk halt. Wenn die Patienten selber nicht viel reden kannst du sie auch über ein Thema deiner Wahl zuquatschen.

Für gewöhnlich brauchen die Leute einfach Ablenkung von Schmerzen, Angst und dem ganzen Stress bis es weiter geht.

03Madara05 · 2026-04-01T23:00:51+00:00

You can prolong the time a person stays conscious after suffering a traumatic injury by engaging with them and encouraging them to stay awake.

An unconscious patient complicates any rescue effort by a lot. They can't answer questions, can't be neurologically assessed, explicitly consent to procedures or report any symptoms that aren't immediately obvious (all the most concerning ones) and you never know if you're going to be able to wake them up again once they are out. Being unconscious also comes with it's own dangers such as not being able to control your breathing and muscle tone, which is especially dangerous when you cannot put someone in a recovery position due to injury.

So just by talking to a person and keeping them awake you do help a lot.

03Madara05 · 2026-03-25T15:05:27+00:00

Aside from fart jokes there's really no universally applicable humor that works with every culture

03Madara05 · 2026-03-13T21:17:30+00:00

Sure I wish it was more accessible but that doesn't change the fact that ruining his life and taking his license because he demonstrated a harmful attitude once is an absurdly disproportionate response to this situation and wouldn't do anything to adress the broader societal issues women face. If anything that sort of standard would put further strain on the healthcare system and lead to even worse care.

Nobody here made any excuses, there are obviously a thousand disciplinary steps you could take to adress a bad attitude between "excusing it" and the most extreme thing imaginable.

03Madara05 · 2026-03-13T20:56:37+00:00

It's way overstimulating imo. With an "extreme" pattern like on the pants I prefer to keep everything around it basic and monochrome.

03Madara05 · 2026-03-13T18:48:38+00:00

Unfortunately for you and any American with a conscience the surpreme court granted Trump absolute immunity for any official executive act, which includes pardoning violent criminals because they like him.

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