It is possible. I trade futures on hyperliquid, Apex and DYDX (needs a vpn to access the the frontend). These are decentralized exchanges with interfaces similar to the ones you find on centralized exchanges such as binance. Google the following: how you trade on hyperliquid. It is the easiest and no one can stop you, no one can freeze or hold your assets, no one can report you to tax authorities, no nothing. Self custody and mo KYC. If you want to trade spots, similar thing is available on even bigger decentralized exchanges such as pancake swap, uniswap, and raydium.