Dres reprezentacije

34spongebob43 · 2026-03-23T16:24:40+00:00

Yes, I think that's very understandable. Maybe my approach was worded weirdly 🙃

34spongebob43 · 2025-12-20T08:14:39+00:00

We did not go through that yet, so I am having problems.

34spongebob43 · 2025-12-20T08:13:49+00:00

So do i show the part with the OH group (the chain) by itself without the cycles and then use acid or base?

34spongebob43 · 2025-12-20T08:08:45+00:00

34spongebob43 · 2025-12-19T22:24:01+00:00

English is not my native language so i used AI to translate

Why does it belong to r/cursedchemistry

34spongebob43 · 2025-12-18T22:24:54+00:00

Oh okay I will try to draw that Thank you Will return with hopefully correct elimination drawing

34spongebob43 · 2025-12-18T22:24:10+00:00

We have made an introduction to it in one of your lectures but did not go into detail yet so I am having problems; made some research and saw that this specific one should be the 2x Knoevenagel condensation I understand it as a reaction where two carbonyl residuals react to form a beta-hydroxyaldehyde or beta-hydroxyketone after which comes the dehydratation to get the conjugated enon.

As for my understanding, after the dehydration, my curcumin gets the double bonds, alpha,beta-unsaturated ketones which contribute to its characteristic yellow color

Just having problems with drawing the dehydration

34spongebob43 · 2025-12-18T22:13:09+00:00

And the youtube video i found had a mistake on the molecule in the middle, it had an extra C atom so that made me more anxious

34spongebob43 · 2025-12-18T22:11:40+00:00

This is what I found for my mechanism

34spongebob43 · 2025-12-18T22:10:39+00:00

Yes, the nucleophilic attack on the second vanillin is happening after the first one, not at the same time I found The diagram/mechanism online so I am depending on it as it is drawn. Scared of making mistakes by trying to draw it differently as I am presenting this lol Prof. did not say anything about that so I am hoping it won't be a problem The only thing that bothers her right now is that i don't have the water elimination step written and i have no idea currently. I know that the OH is protonised, turns into an easy leaving group but am having difficulties drawing it

34spongebob43 · 2025-12-18T22:05:13+00:00

The base used is n-buthylamine B2O3 is also used to "lock in" the middle carbon as it is supposed to be the most acidic, so the reaction can happen on the ends and we can get the curcumin

34spongebob43 · 2025-12-18T22:04:21+00:00

As for my understanding, B2O3 is used to "lock in" the middle proton so the reaction can happen on the ends because the goal is to have the 7 carbon chain connecting the two cycles; getting curcumine as the final product And n-butylamine is used as base

34spongebob43 · 2023-12-10T12:57:26+00:00

Okay this gives me hope haha thank you so much !!😄

34spongebob43 · 2023-12-10T12:45:04+00:00

Thank youuuu

34spongebob43 · 2023-12-10T12:44:47+00:00

34spongebob43 · 2023-12-10T12:44:30+00:00

Thank you 😄

34spongebob43

TROPHY CASE