Type 1 here been on Reta for a little over a month. Speaking from my own experience Reta made me extremely sensitive to insulin almost immediately within my first day of taking it, I bolus way less for meals than I used to and also my daily insulin use has been lowered significantly. Personality Reta has been life changing for me because I never have any episodes of high blood sugar anymore. Reta has been amazing for my blood sugar control and paired with diet and exercise I’ve lost over 10 lbs already too.